International scientific journal "Science and Innovation"

Series D Volume 2 Issue 4


FEATURES OF GROWING SUNBERRY IN THE SOUTHERN CONDITIONS OF UZBEKISTAN

Azamat Rahmatillayevich Khaidarov

Many cultivated plants of the Solanaceae family, when grown in the open ground of Uzbekistan, are affected by pests and diseases. There is evidence in the literature that Sunberry nightshade plants, when grown outdoors, can be damaged by the Colorado potato beetle and aphids. Information on the resistance of Sunberry nightshade to viral, bacterial and fungal diseases when grown outdoors in Uzbekistan. This article discusses the issues of growing sunberry in the South of Uzbekistan.

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DETERMINATION OF PREDISPOSITION TO DISEASES OF THE PERITONEUM AFTER ABDOMINAL SURGERY IN CHILDREN

Berdiyev Ergash Abdullayevich, Rakhmonov Feruz, Tursunboev Kurban, Toshboev Sardor

The authors studied one of the pathogenetic factors of adhesive disease in 53 sick children, predisposition to adhesive diseases and measures to prevent premature formation of adhesions. Predisposition to adhesive disease is observed in 50% of patients and is determined by the degree of increase in the concentration of fibrinogen in the blood and a decrease in fibrinolysis. Appropriate mitigation measures were taken and the possibility of early prevention of adhesions was studied.

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TYPE 2 DIABETES: TIME TO CHANGE THE CONCEPT

Xolliyev Abduvali, Sadarov Otabek, Egamberdiyev Asilbek, Daminov A.T.

Diabetes mellitus (DM) as a concomitant disease with COVID-19 is considered as one of the significant risk factors for the development of adverse outcomes due to a more severe course of infection in conditions of hyperglycemia and other aggravating factors in these patients, such as older age, obesity, and a high incidence of comorbidities (hypertension, cardiovascular disease).

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INFLUENCE OF CHRONIC INTOXICATION WITH THE ORGANOPHOSPHORUS PESTICIDE ANTIO ON THE ACTIVITY OF RAT LYMPHOCYTE ACETYLCHOLINESTERASE

Khaydarova Dilorom Safoevna

Chronic poisoning of rats with the organophosphate pesticide antio at doses of 3.5 mg/kg/day and 17.5 mg/kg/day (1/100 and 1/20 LD50, respectively) in the experiment revealed the presence of acetylcholinesterase activity in their lymphocytes. The results of the experiment showed that the activity of acetylcholinesterase is not the same in different subpopulations of lymphoid cells. The revealed dose-dependent inhibition of acetylcholinesterase in rat lymphocytes during chronic administration of the organophosphorus pesticide antio suggests that there may be a previously unknown mechanism of the immunosuppressive effect of organophosphorus compounds, implemented through the interference of these drugs in the processes of neurotransmitter regulation of the functions of lymphoid cells

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MODERN APPROACHES TO THE MANAGEMENT OF PREGNANT WOMEN WITH UTERINE SCARS AND DELIVERY TACTICS IN THEM

Kurbaniyazova Venera Enverovna

The problem of childbirth in women with a scar on the uterus after previous CK is of great concern and great interest among obstetricians and gynecologists around the world today, because the number of CK operations, including planned operations, is increasing every year. is increasing, but maternal and perinatal mortality is not only not decreasing, but on the contrary, it is increasing [2, 30]. According to the literature, about 30% of women plan to become pregnant again after cesarean section. According to the authors, after discharge from the obstetric hospital, each postpartum woman was informed about the instructions for surgery, the duration of labor and the duration of the water-free period before the operation, the method of KK, the type of incision in the uterus, the method of suturing, the suture used. material, complications during surgery, the amount of blood loss and the delay of the postoperative period should be an exchange sheet. This information is necessary for the selection of candidates for subsequent vaginal delivery [14].

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DIAGNOSTIC VALUE OF PROCALCITONIN IN COVID-19 DISEASE

Ergasheva Munisa Yakubovna, Subxonova Sarvinoz Komilovna

After the onset of the COVID 19 pandemic, there was a need for reliable biomarkers that reflect the rapid progression of the disease to stratify high-risk patients. There is an increased demand for the use of biomarkers that reflect cell and organ damage in the disease of SOVID 19. Plasma biomarkers reflecting bacterial inflammation in the body, including C-reactive protein (CRO) and procalcitonin (PKT) in the diagnosis of bacterial pneumonia, have taken a firm place in the management algorithm of patients with bacterial infection [1,3]. However, since COVID 19 is an understudied disease, further research is needed to develop practical recommendations. It is known that the level of CRP is related to the severity of the course, the spread of inflammatory infiltration, and the prognosis of community-acquired bacterial pneumonia, with its concentration > 100 mg / l, the specificity of confirming bacterial pneumonia reaches 90%, with a concentration < 20 mg / l, the diagnosis is unlikely [1 ,2]. At the beginning of the COVID 19 pandemic, the high level of CRO in the blood of patients is often considered a marker of an infection that is considered to be bacterial, and can be the basis for prescribing antibacterial therapy. Also, high levels of procalcitonin, D-dimer, and ferritin in the blood of patients indicate that a systemic inflammatory reaction is starting in the body. An increase in the level of CRO in the body is related to the severity of the disease and is also one of the main criteria for prescribing anti-inflammatory therapy [2, 4,5]. In addition, it is important to analyze the practical possibilities and prospects of using PKT in bacterial infections - acute pneumonia and infection with the new coronavirus. Procalcitonin is a polypeptide that is normally produced in the cells of the thyroid gland and its concentration in healthy people should not exceed 0.01 ng/ml.

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HUMAN ECOLOGY AND FACTORS AFFECTING THE EXTERNAL ENVIRONMENT ON THE HUMAN BODY

Rasulov Ilkhom Makhmudovich, Hamidov Avazjon Odilovich, Gulom Bekmirzaev

Based on the decree of the President of the Republic of Uzbekistan No. PD-76 "Ecology and Environment" which dated December 30, 2021, so it was designated as the International Day of Environmental Protection on 5 June. As part of the celebration of this day, the UN informs the international community about environmental problems that are urgent worldwide and calls on the peoples of the world to solve these problems. "Ecology and Environment" states that awareness and conscious engagement of each individual is one of the most important issues in strengthening the ecological situation, and studies the basis of human health. In the article, human ecology or anthropoecology is the central part of social society, its socio-natural and natural-scientific basis. Human ecology summarizes relevant views of demography, medicine, morphology, anthropology, and genetics

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MEDICINAL VALUE OF CORNUS MAS L. AND FLAVONOID COMPOSITION OF FRUITS

Matkarimova Gulnaz Maksudzhanovna

Kizil plant is one of the promising vitamin-rich medicinal plants being introduced in our country. Red is used in the food, pharmaceutical industry, as a decoration in folk medicine, and in the preparation of household items. It is widely used in medicine to prevent and treat many diseases. Therefore, it is important to study the chemical composition of these species.

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HOW DOES OBSESSIVE-COMPULSIVE DISORDER MANIFEST ITSELF?

Khudaiberdieva Dilorom Khaidar qizi

This article examines the causes of obsessive-compulsive disorder in people of different ages, and what factors trigger its occurrence. It also shows how it occurs in teenagers and its symptoms.

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PREGNANCY WITH CONGENITAL HEART DISEASE

Sarkisova Victoria Vladimirovna, Muradova Emma Vladimirovna, Saurabh Singh, Aman Bugalia

Congenital heart disease (CHD) is a defect in the structure of the heart and large vessels diagnosed from the moment of birth. The frequency of occurrence varies widely and ranges from 2.4 to 14.15%. Every year, more than 30,000 children with congenital heart defects are born worldwide. For one million of the adult population, there are about 3,500 people with this pathology. Many of these patients are young women planning to carry a pregnancy and give birth to a healthy child [1,2]. In Western countries, congenital heart defects are the most common form of cardiovascular diseases that complicate the course of pregnancy and childbirth. 74% of cases of complications were registered according to the Canadian CARPREG registry and 66% of complications according to The European Register ROPAC.

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