INFLUENCE OF CHRONIC INTOXICATION WITH THE ORGANOPHOSPHORUS PESTICIDE ANTIO ON THE ACTIVITY OF RAT LYMPHOCYTE ACETYLCHOLINESTERASE Abstract: Chronic poisoning of rats with the organophosphate pesticide antio at doses of 3.5 mg/kg/day and 17.5 mg/kg/day (1/100 and 1/20 LD50, respectively) in the experiment revealed the presence of acetylcholinesterase activity in their lymphocytes. The results of the experiment showed that the activity of acetylcholinesterase is not the same in different subpopulations of lymphoid cells. The revealed dose-dependent inhibition of acetylcholinesterase in rat lymphocytes during chronic administration of the organophosphorus pesticide antio suggests that there may be a previously unknown mechanism of the immunosuppressive effect of organophosphorus compounds, implemented through the interference of these drugs in the processes of neurotransmitter regulation of the functions of lymphoid cells

MODERN APPROACHES TO THE MANAGEMENT OF PREGNANT WOMEN WITH UTERINE SCARS AND DELIVERY TACTICS IN THEM Abstract: The problem of childbirth in women with a scar on the uterus after previous CK is of great concern and great interest among obstetricians and gynecologists around the world today, because the number of CK operations, including planned operations, is increasing every year. is increasing, but maternal and perinatal mortality is not only not decreasing, but on the contrary, it is increasing [2, 30]. According to the literature, about 30% of women plan to become pregnant again after cesarean section. According to the authors, after discharge from the obstetric hospital, each postpartum woman was informed about the instructions for surgery, the duration of labor and the duration of the water-free period before the operation, the method of KK, the type of incision in the uterus, the method of suturing, the suture used. material, complications during surgery, the amount of blood loss and the delay of the postoperative period should be an exchange sheet. This information is necessary for the selection of candidates for subsequent vaginal delivery [14].

DIAGNOSTIC VALUE OF PROCALCITONIN IN COVID-19 DISEASE Abstract: After the onset of the COVID 19 pandemic, there was a need for reliable biomarkers that reflect the rapid progression of the disease to stratify high-risk patients. There is an increased demand for the use of biomarkers that reflect cell and organ damage in the disease of SOVID 19. Plasma biomarkers reflecting bacterial inflammation in the body, including C-reactive protein (CRO) and procalcitonin (PKT) in the diagnosis of bacterial pneumonia, have taken a firm place in the management algorithm of patients with bacterial infection [1,3]. However, since COVID 19 is an understudied disease, further research is needed to develop practical recommendations. It is known that the level of CRP is related to the severity of the course, the spread of inflammatory infiltration, and the prognosis of community-acquired bacterial pneumonia, with its concentration > 100 mg / l, the specificity of confirming bacterial pneumonia reaches 90%, with a concentration < 20 mg / l, the diagnosis is unlikely [1 ,2]. At the beginning of the COVID 19 pandemic, the high level of CRO in the blood of patients is often considered a marker of an infection that is considered to be bacterial, and can be the basis for prescribing antibacterial therapy. Also, high levels of procalcitonin, D-dimer, and ferritin in the blood of patients indicate that a systemic inflammatory reaction is starting in the body. An increase in the level of CRO in the body is related to the severity of the disease and is also one of the main criteria for prescribing anti-inflammatory therapy [2, 4,5]. In addition, it is important to analyze the practical possibilities and prospects of using PKT in bacterial infections - acute pneumonia and infection with the new coronavirus. Procalcitonin is a polypeptide that is normally produced in the cells of the thyroid gland and its concentration in healthy people should not exceed 0.01 ng/ml.

ABOUT THE WORDS ADOPTED FROM THE FRENCH LANGUAGE INTO THE UZBEK LANGUAGE Abstract: Pronunciation of words derived from foreign languages. First of all, it should be mentioned that words borrowed from Uzbek to another languages, such as Russian, Arabic or Persian, do not have their original Uzbek pronunciation, but their pronunciations are adapted to the pronunciation standarts of those languages. For example, the Uzbek words, “oqsaqol”, “qarovul”, “tog'a” are pronounced in Tajik as “aksaqol”, “karovul”, “tago”, or the Uzbek words “tanga”, “qishloq”, “o'rik” are pronounced as “dengi”, “kishlak”, “uryuk” in Russian. Signs of becoming dependent on the pronunciation norms of other languages, in particular, English, is appearing without getting rid of the dominance of the Russian pronunciation in our mother tongue established in the Soviet era.

COMPARATIVE ANALYSIS OF SOMATIC PROVERBS IN UZBEK AND ENGLISH LANGUAGES Abstract: This scientific article talks about the specific features of somatic proverbs in Uzbek and English languages. The linguocultural aspect of linguistics is taken into account when conducting research on the comparison of proverbs of languages. Paremia was highlighted as an important component of the analysis

HOW WE CAN IMPROVE TO LEARN ANOTHER FOREIGN LANGUAGE Abstract: Make realistic, specific goals You have decided to learn another language. Now what? On our recent live chat our panellists first piece of advice was to ask yourself: what do you want to achieve and by when? Donavan Whyte, vice president of enterprise and education at Rosetta Stone, says: “Language learning is best when broken down into manageable goals that are achievable over a few months. This is far more motivating and realistic.”

PHYSIOLOGICAL REQUIREMENTS AND THEIR FULLFILMENT FOR MACRO AND MICRONUTRIENS OF ACADEMIC LYCEUM AND HIGH SCHOOL STUDENTS IN SOUTHERN PART OF UZBEKISTAN Abstract: The article analyzes the content of macro- (proteins, fats, carbohydrates) and micronutrients (vitamins, minerals) in the daily diet of students of academic lyceums and high schools in Karshi and Termez on the basis of special tables. According to the results of the analysis, the proteins, fats and vitamins in almost all nutrients in the daily diet of students are significantly lower than the norm, and the amount of carbohydrates and minerals in most foods is higher than the norm.

THE PROBLEM OF CREATIVITY AND ITS FORMATION IN YOUNG PEOPLE Abstract: Through this article, the author expressed his opinion about the characteristics of creative thinking of young people in finding their place in society and their self-awareness and the unconventionality of the thinking process, some features of its formation

GIS TECHNOLOGIES IN MODERN GEOGRAPHY EDUCATION Abstract: At various stages of the development of society, terms such as computerization, educational information, geographic information technologies, and geographic information systems began to appear. The article describes the issues of modeling the geographic space and improving the effectiveness of the educational process using GIS in the geography teaching methodology

THE ROLE OF ADVANCED TECHNOLOGY IN TEACHING ENGLISH IN INCLUSIVE EDUCATION Abstract: This article presents modern approaches and innovations in teaching English in elementary grades as a result of the application of methods, students develop logical thinking skills, improve speech, form the skill of a quick and correct answer, awaken a passion for knowledge, a desire for thorough preparation for lessons. This gives access to innovative learning technologies and increases demand. Currently, ensuring the quality of teaching foreign languages to the younger generation, radically improving the system of training specialists who are fluent in foreign languages, training mature personnel who meet international educational standards by mastering foreign languages is one of the goals of the educational reform being carried out in the country.