ALGORITHMS FOR INTELLIGENT DIAGNOSIS OF A PATIENT WITH HEART DISEASE: AN OVERVIEW Abstract: Heart diseases stand as a leading cause of mortality worldwide, posing a particularly severe challenge in developing regions across Africa and Asia. Detecting heart diseases in their early stages not only empowers patients to take preventive measures but also equips healthcare practitioners to discern and mitigate the primary causes before an actual heart attack occurs. This paper introduces CardioHelp, a method devised to predict the likelihood of cardiovascular disease in patients. This method integrates a deep learning algorithm known as convolutional neural networks (CNN), specifically focused on temporal data modeling for early-stage heart failure prediction.

SOFTWARE TOOLS AND THEIR CAPABILITIES FOR TEACHING FUTURE PRIMARY SCHOOL TEACHERS TO CREATE 3D INTERACTIVE INFORMATIONAL EDUCATIONAL RESOURCES Abstract: The article presents an analysis of the possibilities, shortcomings and areas of application of software tools for creating 3D interactive informational educational resources for future primary school teachers.

THE INTENSITY OF POST-VACCINATION IMMUNITY TO PERTUSSIS INFECTION IN CHILDREN WITH HEALTH ABNORMALITIES Abstract: Whooping cough is an acute infectious bacterial disease, the main symptom of which is a paroxysmal cough, characterized by a rather severe clinical course, as well as often the development of serious complications from the respiratory and nervous systems in children of different ages. The article presents the results of an analysis of the incidence of whooping cough and the quality of vaccine prevention according to seromonitoring data of 111 children, of which 76 children with health problems aged from 3 to 10 years, 34 boys (44.74%) and 42 girls (55.26%). ) vaccinated against whooping cough, on an individual schedule, in a family clinic. The control group consisted of 35 relatively healthy children. The work assessed the immunological activity in children with health problems vaccinated against whooping cough. Determination of class G (IgG) antibody titers using enzyme-linked immunosorbent assay (ELISA). Sera with IgG antibody levels above 11 units were considered seropositive. The results of the study showed that in the 76 children we examined with health problems, 2/3 were patients with frequent acute respiratory viral infections 48(63.16±1.21%) (P<0.05). When vaccinating against whooping cough in children with health problems and a high incidence of previous diseases, the level of anti-whooping cough antibodies was 27.63% of children. Recommendations are presented that an inadequate immune response to vaccination against whooping cough in children with health problems allows us to consider such children as a group at increased risk for ineffective vaccination and justifies the need to use individual tactics when immunizing them.

DEVELOPMENT OF LEFT VENTRICULAR HYPERTROPHY IN ARTERIAL HYPERTENSION: ANALYSIS OF SCIENTIFIC RESEARCH Abstract: This article presents an analysis of scientific studies on the development of left ventricular hypertrophy in the context of arterial hypertension. Arterial hypertension is a risk factor for the development of various cardiovascular complications. Key points discussed in the article include analysing the relationship between arterial hypertension and left ventricular hypertrophy. The research data also covers the study of left ventricular mass and left ventricular mass index in patients with arterial hypertension. The analysis highlights the importance of blood pressure control in preventing the development of cardiovascular disease

THE USAGE OF PROBIOTICS ENTEROL IN COMBINED THERAPY OF COLON MICROBIOCENOSIS IN CHILDREN WITH TYPE 1 DIABETES MELLITUS Abstract: The article presents the results of studying the efficacy of probiotic Enterol in the complex therapy of patients with intestinal microbiocenosis type 1 diabetes mellitus. To accomplish the results of clinical and bacteriological examination of 33 children with type 1 diabetes aged 10 to 18 years. Aim. The purpose of the study was to study the use of the probiotic enterol in the complex therapy of intestinal microbiocenosis disorders in order to correct the intestinal microbiome in patients with type 1 diabetes mellitus. Materials and methods. To accomplish the results of clinical and bacteriological examination of 33 children with type 1 diabetes aged 10 to 18 years. The analysis of the effectiveness of probiotic Enterol in the complex therapy of patients with intestinal microbiocenosis type 1 diabetes. The control group consisted of 30 healthy individuals. Conclusions. Conducts bacteriological analysis of the intestinal microflora. All of the surveyed children with type 1 diabetes, in the intestinal microflora are disbiotic changes. The results indicate the feasibility of active correction dysbiotic changes in diabetes mellitus type 1 enzyme preparations such as enterol.

PECULIARITIES OF USING POLYOXIDONIUM DRUG IN CHILDREN WITH CHRONIC OBSTRUCTIVE BRONCHITIS Abstract: The article includes information on modern approaches to the treatment of children with chronic obstructive bronchitis, current national and foreign protocols for the treatment of obstructive bronchitis. In detail, therapy-based approaches to the oral administration of the tablet form of a polyoxydonium drug are discussed. When polyoxydonium is taken in a dose of 6 mg for 5 days, the period of prolongation of broncho-obstructive syndrome in chronic bronchitis, the duration of treatment in the stationary state can be reduced and the patient's condition can improve faster.

DEVELOPMENT FEATURES OF FAMILY, CONGENITAL GLAUCOMA Abstract: This article is devoted to studying the features of the development of congenital glaucoma in children with familial glaucoma. The authors examined two families with familial, congenital glaucoma. The patients were treated as inpatients in the eye department of the clinic of the Tashkent Pediatric Medical Institute

ANTIRADICAL ACTIVITY OF LOCAL STRAINS OF LACTOBACILLI Abstract: The antiradical properties of local Lactobacillus strains were investigated using the free radical inhibition method of 1,1-diphenyl-2-picrylhydrazyl (DPPH). It was shown that both culture fluid and intact cells of the investigated caused a decrease in the level of DFPH radicals. The highest antiradical activity (41.9%) was demonstrated by Lacticaseibacillus rhamnosus AK 2.2: the inhibitory ability of the supernatant, is - 69.28%, and in intact cells is - 25.6%.

USE OF ANTIHYPERTENSIVE DRUGS DURING PREGNANCY Abstract: Guidelines for the classification, diagnosis, and treatment of hypertensive disorders (including preeclampsia) are available from the American College of Obstetricians and Gynecologists (ACOG [ 1 ]). In 2017, the American College of Cardiology (ACC) and the American Heart Association (AHA) published new guidelines for evaluating high blood pressure (BP). When determining hypertension, they lowered the blood pressure limits as follows: Normal < 120/80 mm Hg. Art. Elevated: 120-129/< 80 mm Hg. Art. Stage 1 hypertension: 130-139 / 80-89 mm Hg. Art. Stage 2 hypertension: ≥ 140/90 mmHg. Art.

ETIOLOGICAL FACTORS OF HEARING ANALYZER IMPAIRMENT AND REHABILITATION OF CHILDREN WITH HEARING IMPAIRMENT USING COMPUTER PROGRAMS (LITERATURE REVIEW) Abstract: As you know, a healthy child perceives the world around him through five senses: sight, hearing, smell, taste and touch. Among the five senses, vision and hearing are the most important for a person: it is through them that we receive maximum information about the environment. If for some reason a child loses any of them, then he develops a feeling of lack of information.