The article presents examination data of 70 children with tic hyperkinesis.Tic hyperkinesis affects the cognitive and emotional spheres, and these changes are most pronounced with common tics. Based on the Toulouse-Pieron test, which characterizes the ability to voluntarily concentrate attention, it has been proven that children with local tics have a significantly higher concentration of attention compared to common ones.
13.03.2024 Volume 3 Issue 3 View more Download
The article reveals the negative effects of phytotoxins of pathogenic fungi found in chickpea on plant fertility, growth and development. Fungi causing root rot, fusarium wilt and ascochyta diseases of peas were studied experimentally. Phytotoxins produced by the fungi Rhizoctania solani, Fusarium oxysporum, and Ascochyta rabiei have all been found to have a negative effect on pea seed germination. It has been stated that if timely control measures are not applied to a chickpea plant infected with fungi, it will have a negative effect on productivity
13.03.2024 Volume 3 Issue 3 View more Download
The results of our own study of weight correction, metabolic and immunopathological disorders in overweight and obese adolescent children are presented. Aim: Development of a treatment and preventive program for weight correction, metabolic and immunopathological disorders in overweight and obese children. Materials and methods: 60 adolescents were examined: 40 with exogenous constitutional obesity of the first degree, 20 with overweight. Studies were carried out on the levels of adiponectin, highly sensitive C-reactive protein, lipid spectrum in the blood plasma, as well as bacteriological examination of feces. The developed treatment and preventive program was applied to 50 children, divided into 4 groups: the main ones - 20 obese children (1) and 10 overweight children (2), who received a course of probiotic medication as part of the developed treatment and preventive program. The control groups included 20 obese children (3) and 10 overweight children (4), who, for a number of reasons (parental abandonment, child abandonment, financial situation in the family), did not receive a probiotic drug as part of the weight correction program. The results were assessed after 6 and 12 months, with repeated paraclinical studies. Results: Assessment of the level of CRP-hs after 12 months of application of the developed treatment and prophylactic program demonstrated a decrease in the activity of CRP-hs and an increase in the level of adiponectin (from 4.06 ± 0.06 to 2.4 ± 0.03 and from 5.0 ± 0 .13 to 12.23±0.08 mg/ml, respectively), a significant (p <0.05) decrease in total cholesterol levels (from 6.09±1.07 to 4.85±0.93 mmol/l) and triglycerides (from 2.05±0.17 to 1.12±0.29 mmol/l), as well as normalization of the quantitative and qualitative composition of the intestinal microbiota, the degree of dysbiotic disorders and the disappearance of signs of bacterial contamination in the main groups of children, compared with the control in groups. Stabilization of body weight, disappearance of signs of metabolic and immunopathological disorders after 12 months of use of the developed treatment and preventive program in the complex treatment of obesity allow us to recommend its use in both group and individual treatment.
13.03.2024 Volume 3 Issue 3 View more Download
Acute intestinal infections continue to be the most common diseases of childhood after acute respiratory viral infections and are relevant for pediatrics, leading to the development of severe forms of the disease and affecting the further development of the child. [1,2,3]. Among the etiological factors of acute diarrhea, the leading place is occupied by diseases of viral etiology, which accounted for 50%, and the most significant are rotaviruses (36%), noroviruses (17%) [4,5]. Bacterial diarrhea (12%) is dominated by Salmonella (9%), Shigella (5%), Campylobacter (5,5%), Escherichia and opportunistic bacteria, and in 50-80% of cases, acute diarrhea (AD) in children remains etiologically undeciphered [6,7]. One of the areas that requires in-depth study is the assessment of the clinical course of AD in young children, depending on the age and outcome of the disease.
13.03.2024 Volume 3 Issue 3 View more Download
Congenital heart defects are one of the most common congenital anomalies in children (30% of all congenital malformations); they are the third most common after congenital pathology of the musculoskeletal system and central nervous system. In this regard, it was of interest to study the most likely risk factors for the formation of congenital heart defects in children. Purpose of the study. To study the risk factors for the formation of congenital heart defects in children based on an analytical review of medical records - 56 children with congenital heart defects hospitalized in the cardiology department of the National Children's Medical Center of the Republic of Uzbekistan. Materials and methods. Analytical review of medical documentation (56 patients with congenital heart defects hospitalized in the cardiology department of the National Children's Medical Center of the Republic of Uzbekistan. The control group consisted of 32 children without pathology of the cardiovascular system. Results. Leading risk factors were identified: anemia (48.5%), chronic placental insufficiency (38%), threatened miscarriage (32.7%), toxicosis of the first half of pregnancy (22.3%) and acute viral infection in the early stages of pregnancy (21.3%). Conclusion. The risk of developing congenital heart defects in many cases is due to a combination of hereditary predisposition with a multilateral pathological influence of internal and external environmental factors, the simultaneity of their impact, as well as the duration of exposure to the damaging factor, the number of damaging factors and the simultaneity of their effects.
12.03.2024 Volume 3 Issue 3 View more Download
The indicators used for a comprehensive assessment of the patient's condition include the determination of quality of life (QL) and psychological status (PS), which can exacerbate cardiovascular prognostic factors. The quality of life and psychological disorders were assessed in 54 female and male patients diagnosed with cardiac syndrome X (CSX). It was found that the presence of symptoms of depression is associated with a decrease in QL according to the SF-36 scale. The deterioration of hemodynamic parameters was associated with a worsening of QL, as well as with an increase in anxiety-depressive disorders. In patients with CSX, cognitive function regressed as the severity of the disease increased
11.03.2024 Volume 3 Issue 3 View more Download
Gynecological oncology patients often present with concomitant gynecological pathologies that can complicate the management and treatment of their primary cancer. This review aims to summarize the common concomitant gynecological pathologies encountered in patients with gynecological malignancies, including endometrial, ovarian, cervical, and vulvar cancers. The impact of these concomitant pathologies on treatment outcomes and survival will also be discussed. Understanding and managing these additional gynecological conditions are essential for optimizing the care of patients with gynecological cancers
11.03.2024 Volume 3 Issue 3 View more Download
A new viral infection, called "COVID-19" in the spring of 2020, took on a pandemic character. Data on the impact of Covid-19 on a pregnant woman and fetus are few and contradictory. The aim of the study was to study the clinical and laboratory features of coronavirus infection in pregnant women. An analysis was made of 222 birth histories of women with laboratory-confirmed PCR for COVID-19, sent for delivery to a specialized obstetric department in October-December 2020. The results of our studies showed that 70.2% had a mild form of infection, 21.2% had a moderate form, and 8.1% had a severe form. The frequency and nature of lesions of the upper and lower respiratory tract, SPO2 parameters and lung lesions, as well as the age of pregnant women, parity, and the presence of somatic pathology are presented. Conclusions. In most pregnant women, a severe form of COVID-19 is characterized by bilateral pneumonia with ARS against the background of anemia in 100% of cases. Severe COVID-19 infection was more common in pregnant women aged 35 years and older. The condition of pregnant women with COVID-19 aggravated the development of severe preeclampsia, premature detachment of the placenta, and multiple pregnancies.
05.03.2024 Volume 3 Issue 3 View more Download
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