CHARACTERISTICS OF THE COURSE OF COMPLICATED GESTATIONAL PYELONEPHRITIS IN PREGNANTS
Shopulotova Zarina Abdumuminovna, Bazarova Fariza Ravshanovna, Temirova Riskiyabonu Nazirjonovna
Abstract: Pyelonephritis has a negative effect on the course of pregnancy and the state of the fetus, which is manifested in the risk of miscarriage, premature birth, placental insufficiency, fetal hypoxia, intrauterine infection, preeclampsia, and the complex course of the adaptation period. In pyelonephritis, the pathogenic factor that affects the chronic stage of inflammation loses its leading role, the processes affecting the change in the rheological properties of blood and microcirculation play an important role, which leads to the development of a chronic condition. comes - the causes of this disease are a risk factor for the mother and the fetus and lead to perinatal losses

THE STATE OF GESTATIONAL PYELONEPHRITIS IN SAMARKAND REGION
Khudoyarova Dildora Rakhimovna, Shopulotova Zarina Abdumuminovna, Hayitova Gulira’no Ergashevna, Bazarova Fariza Ravshanovna
Abstract: In pyelonephritis, the pathogenic factor that affects the chronic stage of inflammation loses its leading role, the processes affecting the change in the rheological properties of blood and microcirculation play an important role, which leads to the development of a chronic condition. comes - the causes of this disease are a risk factor for the mother and the fetus, leading to perinatal losses. Patients with acute pyelonephritis have significant changes in the hemostasis system, clinical and laboratory parameters. The above changes increase during the transition from the serous stage to the purulent stage of kidney inflammation

MODERN ASPECTS OF DIAGNOSING GESTATIONAL PYELONEPHRITIS
Shopulotova Zarina Abdumuminovna, Kobilova Zarina Khamzaevna, Bazarova Fariza Ravshanovna
Abstract: In pyelonephritis, the pathogenic factor that affects the chronic stage of inflammation loses its leading role, the processes affecting the change in the rheological properties of blood and microcirculation play an important role, which leads to the development of a chronic condition. comes - the causes of this disease are a risk factor for the mother and the fetus, leading to perinatal losses. Patients with acute pyelonephritis have significant changes in the hemostasis system, clinical and laboratory parameters. The above changes increase during the transition from the serous stage to the purulent stage of kidney inflammation

ETIOLOGY STRUCTURE OF OVERACTIVE BLADDER IN MODERN UROLOGY
Shopulotov Shokhrukh Asliddinovich, Shopulotova Zarina Abdumuminovna, Supkhonov Umar Umedovich
Abstract: Goal of work was studying of etiological factors, occurrence frequency and structure of OBS.

TREATMENT OF COMPLICATED GESTATIONAL PYELONEPHRITIS IN PREGNANTS
Shopulotova Zarina Abdumuminovna, Kobilova Zarina Khamzaevna, Bazarova Fariza Ravshanovna
Abstract: Studying the interaction between gestational pyelonephritis and pregnancy is important due to the high percentage of obstetric complications, negative perinatal outcomes and serious diseases in newborns, which emphasize the medical and socioeconomic importance of the problem. In chronic pyelonephritis, pregnancy is complicated by iron deficiency anemia (35-70%), premature termination of pregnancy at various times (15-20%), chronic placental insufficiency (30-35%), preeclampsia (35-70%). 30-40% causes complications such as chronic uterine hypoxia (30-40%), fetal infection (20-30%) and growth retardation (12-15%). In chronic pyelonephritis, the ability of pregnant mothers to adapt to newborns is significantly impaired and the risk of early neonatal death increases.

A STUDY OF PATIENTS WITH A UTERINE SCAR USING GENERAL CLINICAL TESTS
Shopulotova Zarina Abdumuminovna, Mahmudjonova Sitorabonu Rustamovna, Djumayev Mukhammadjon Djasurovich
Abstract: Cesarean section operation is included in surgical operation of moderate or severe degree. According to information from various sources, complications after CK surgery are 7-19.5% .These complications are explained by obstetric and extragenital pathologies. With the increase in the frequency of cesarean sections, as well as with the improvement in the quality and spread of ultrasound diagnostics, the quality of uterine scar examination has steadily increased from year to year. In recent years, in the literature and at gynecological conferences of the highest level, more and more attention has been paid to such a concept as “niches” in the area of the cesarean section scar. The defect appears as a fluid-filled abnormality in the anterior wall of the uterus at the site of a previous cesarean section

STATISTICAL STUDY OF PATIENTS USING EXAMINATION METHODS
Shopulotova Zarina Abdumuminovna, Mahmudjonova Sitorabonu Rustamovna, Djumayev Mukhammadjon Djasurovich
Abstract: Cesarean section operation is included in surgical Cesarean section operation of moderate or severe degree. According to information from various sources, complications after surgery are 7-19.5%. These complications are explained by obstetric and extragenital pathologies. The first stage lasts an average of 2-7 days from the moment of injury, and its duration depends on the size and type of injury. The developing microcirculation changes depend on changes in vascular tone, impaired permeability of vascular walls, and the nature of biosynthesis of biologically active substances (cyclic nucleotides, prostacyclin, etc.)

BIOLOGICAL TEACHING EFFECTIVENESS, TEACHING AND THE IMPORTANCE OF INTEGRATIVE TEACHING
Ergasheva Nazokat Alisherovna
Abstract: The impact of the integrative approach of students on the quality of students' knowledge and skills has been revealed. In the process of education, it ensures that the process of preparing future biology teachers for professional and pedagogical activity is directly related to the specific features of the integration of pedagogical knowledge. In the content of the article, the ways to acquire knowledge, skills and abilities in the fields of pedagogic theory and methodology, pedagogical technologies, psychology and pedagogical skills are highlighted in the preparation of future biology teachers for professional and pedagogical activities.

INCREASING THE ACTIVITY OF WOMEN IN SOCIETY
Kabilova G.R, Igamberdieva D.A, Shopulotova Z.A, Kobilova Z.Kh
Abstract: Among many developed countries of the world, in the Republic of Uzbekistan, attention to women and children is manifested in the fact that strengthening their place in society and state management is rising to the level of state policy. In this article, it is important to increase the socio-political activity of women in our country, to ensure that their rights and legal interests are fully respected, to support motherhood and childhood in every way, to realize their abilities and opportunities in various fields and industries. information is given about the wide-scale work being carried out to create conditions for its release, as well as to strengthen the institution of the family.

ASSESSING THE PROBABILITY OF FORMATION OF "NICHE" SYMPTOM
Shopulotova Zarina Abdumuminovna, Mahmudjonova Sitorabonu Rustamovna, Djumayev Mukhammadjon Djasurovich
Abstract: With the increase in the frequency of cesarean sections, as well as with the improvement in the quality and spread of ultrasound diagnostics, the quality of uterine scar examination has steadily increased from year to year. In recent years, in the literature and at gynecological conferences of the highest level, more and more attention has been paid to such a concept as “niches” in the area of the cesarean section scar. The defect appears as a fluid-filled abnormality in the anterior wall of the uterus at the site of a previous cesarean section. The niche most often has the shape of a triangle, sometimes a “bag” until the scar becomes incompetent, when the entire thickness of the uterine wall has separated and the “niche” is covered by the vesicouterine fold