The purpose of the study is the current state of Corbicula fluminalis populations distributed in the reservoirs of Uzbekistan consists of teaching malacalogical, ecological research methods and the method of comparative analysis. The aim of the study is to determine the faunal composition of Corbicula fluminalis bivalves in the reservoirs of Uzbekistan and to assess the prospects for their use. Corbicula fluminalis. Status. 2 (VU:D): Weak, shrinking appearance. The state of the C. fluminalis population in the reservoirs of Uzbekistan is the following: P1. Ferghana population of the Syr Darya: 2 – 43%, p=2.6; 3 – 37%, p=2.2; 4 – 20%, p=1.2. P2. Syrdarya population of Syrdarya: 2 – 41%, p=2.8; 3 – 43%, p=2.5; 4 – 16%, p=1.1. P3. Average Zarafshan: 2 – 44%, p=3.3; 3 – 39%, p=2.9; 4 – 17%, p=1.3. P4. Middle Kashkadarya: 2 – 44%, p=2.9; 3 – 38%, p=2.5; 4 – 18%, p= 1.2. P5. Middle Amu Darya: 2 – 40%, ρ=2,4; 3 – 45%, ρ=2,7; 4 – 5%, ρ=0,9. Indicators of the age ratio of the C. fluminalis population are observed in populations distributed in the territory of the Fergana region of the Syrdarya basin, Middle Zarafshan and Middle Kashkadarya. Conclusion In all studied populations of Corbicula fluminalis (Müller, 1774); body parameters (shell length, height, swelling) linearly increase with the age of mollusks. Similar to other members of the Corbicula genus, the active period of the organism’s indicators corresponds to the age of 2-3 years. After the age of 4, they grow very slowly. It should be noted that in the population of Syrdarya region of Syrdarya and Middle Amudarya, shell size does not change after 3 years of age. The smallest biomass of the species in the population corresponds to the contribution of 2-year-old individuals, in which their mass is 59-75 g. but they have the highest density in it during this period. The highest biomass corresponds to the share of 3-year-old individuals of the species in the population.
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Supramolecular complexes of the monoammonium glycyrrhizinate (MG) with amino acids, to name methionine (Met) and DL-carnitine-HCL (Car) and phenolic compounds, to name quercetin (Que) and methoxycinnamic acid (MethA) in molar ratio 4:1, were generated as promising low-dose cytoprotectors/hepatoprotectors. After induction of acetaminophen-induced hepatitis (1500 mg/kg for 2 days intragastrically) and the 7-day administration of complexes, MG/Met and MG/MethA caused statistically significant shortening of duration of hexobarbital-induced sleep at the dose of 2,5 mg/kg (160±14,0 min in control vs 36,1±2,3 and 33,4±2,2 min, respectively, p<0,05 both) and duration of thiopental-induced sleep at the dose of 5 mg/kg (63,5±4,2 min in control vs 20,7±1,6 and 17,7±1,2 min, respectively, p<0,05 both); MG/Car and MG/Que at the dose 5 mg/kg caused the most significant reduction in activity of the enzyme alkaline phosphatase (245,2±16,4 U/l in control vs 88,33±4,67 and 96,13±4,27 U/l, respectively, p<0,05 both). According to histological studies MG/Met and MG/MethA at the dose of 5 mg/kg caused more significant reduction in the dyscirculatory and edematous events; signs of activation of lymphoid and macrophagal cells in the liver tissue appeared. Under normal physiological conditions, the complexes under study were not found to produce any effects on the bile secreting function of the liver. These findings demonstrate necessity to generate a complex medication combining various effects indispensable for recovery of various functions of the liver after acute injuries, toxic effects of xenobiotics, as well as for prevention of grave complications of hepatitis
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Milk and dairy products are products of daily consumption. They belong to a group and accompany man throughout his life - from birth from the first days to old age. First of all, it is the irreplaceable mother's milk fresh. For the newborn - then cow's milk and products based on it. Meanwhile, goat's milk products are produced. Dairy products in the human diet their role cannot be overemphasized. The great Russian scientist Academician I.P. Pavlov called milk "nature". He called it the most marvelous and perfect dish prepared by himself. Fortification of dairy products with vitamins. Information on vitamin fortification of dairy products around the world.
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The study of the genetic and biochemical basis of the problem of the formation of post-acne scar changes, as well as the establishment of significant molecular genetic and biochemical markers is almost at the very initial stage of development⁷᾿⁸᾿⁹᾿¹⁰᾿¹¹᾿¹²᾿¹³. Recently, the literature very often states the presence of a pathogenetic connection between unfavorable genotypes with the formation of an atrophic form of post-acne¹, which became the goal of our study. Of these, works devoted to assessing the significance of the 1997C/A polymorphism of the COL1A1 gene (including indirectly) in the formation of post-acne scar changes are limited to single studies¹᾿¹⁴᾿¹⁵᾿¹⁶ In addition to these, there are works devoted to the role of epigenetic factors in disruption of COL1A1 collagen synthesis and the development of scars post-acne¹⁷᾿¹⁸᾿¹⁹. At the same time, our results are consistent with the data of the above researchers
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Difficulties in diagnosing acute appendicitis during pregnancy are associated with impaired microcirculation, stagnation in the appendix due to stretching of the anterior abdominal wall and pressure of the enlarged uterus on the intestinal walls. This article covers modern issues of diagnosis and treatment of acute appendicitis in pregnant women, the difficulties of diagnosing this pathology in the first, second and third trimester of pregnancy, management of patients in the postoperative period, prolongation of pregnancy and discusses issues of delivery after appendectomy. An analysis of the case histories of 70 patients with acute appendicitis during pregnancy was carried out. appendectomy at various stages of pregnancy. The information value of ultrasound examination and diagnostic laparoscopy for acute appendicitis in pregnant women is assessed. Ultrasound and laparoscopic signs of acute appendicitis are described. A scheme of treatment and diagnostic algorithm for acute appendicitis in pregnant women has been developed.
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Cardiovascular diseases (CVD) are the leading cause of death in many countries. Taking into account the multifactorial etiology of CVD, the close association of risk factors (FR) with each other and the mutually reinforcing effect, their impact on health began to be considered not individually, but in total. The main task of preventive measures is to identify FR, assess the degree of total cardiovascular risk and reduce it in people with increased risk (by modifying all available FR), as well as recovery in order to maintain low risk in people with a low probability of developing the disease.
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In recent decades, the problem of the relationship between oral health and cardiovascular diseases has been considered very relevant. The influence of foci of chronic oral infection on the development of common diseases is recognized as significant in all countries of the world (WHO, 2003). Thus, according to the World Health Organization, based on dental examination of the population, periodontal diseases occur in 68-98%. The incidence of periodontitis reaches 98.5% by the age of 40. The number of people suffering from cardiovascular diseases is also high all over the world. In developed countries, cardiovascular diseases remain the main cause of death. According to WHO, 14 million people die from CVD every year. According to the Cardiological Society, the mortality rate from ischemic heart disease in people aged 35 to 64 years in our country turned out to be the highest in Europe and amounted to more than 350 for men, and more than 100 per 100,000 people per year for the general population. Periodontal diseases are an important medical and social problem, characterized by constant growth and widespread prevalence in people not only the elderly, but also young people. An important feature of the functioning of organs and tissues of the oral cavity is the fact that all ongoing processes are carried out in the constant presence of various associations of microorganisms that are either the cause or participants in pathological processes in the body [1.3.5.7.9.11.13].
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Spinal anesthesia in children has many potential benefits. However, performing spinal anesthesia in children, especially infants, has certain technical difficulties. For more than a century, the technique of performing spinal anesthesia has been based on landmarks and has not changed for many years. Advances in ultrasound technology may provide an opportunity to improve spinal procedures in infants. But the traditional approach in some cases may not be reliable because these surface landmarks may be absent, unclear, or distorted in the presence of obesity, previous spinal surgery, deformities, or degenerative changes. Manual palpation may be inaccurate, and placement of the needle at or above the level of the conus medullaris can lead to complications, including neurological injury. Although rare, spinal cord injury resulting from direct needle trauma or intramedullary injection of local anesthetic can be potentially fatal. Ultrasonography makes it possible to more accurately select the appropriate intervertebral space for spinal anesthesia, reduce the technical complexity of neuraxial blockade, and minimize the number of attempts at lumbar puncture. Multiple attempts at needle insertion may increase the risk of complications such as post-puncture headache and back pain
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Predicting adverse outcomes in people who have suffered a myocardial infarction remains a serious and unresolved problem, which pushes researchers to search for new technologies. One of the relatively promising new noninvasive methods for predicting sudden coronary death in patients with coronary artery disease and ventricular arrhythmias may be a noninvasive assessment of myocardial electrical instability. Taking into account its important prognostic role, primarily in patients with ventricular arrhythmia who have suffered a myocardial infarction and have a multivessel character of coronary lesion, the purpose of this work was to study the characteristics of QT interval variance and heart rate variability in this category of patients.
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In this article, we analyze the application of artificial intelligence (AI) in construction project management based on current research and practical examples. Our aim is to explore various aspects of AI application in construction, identify its main advantages and capabilities, and evaluate its impact on project management effectiveness and work quality. Through our analysis, we have found that the use of AI in construction project management contributes to process optimization, improved planning and control, and enhanced safety on construction sites. The research also leads to the conclusion that AI has the potential to significantly improve the performance and efficiency of construction work overall.
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SCIENCE & INNOVATION