Firstly, before I delve into the subject let us understand what does it mean to be healthy and how does one’s lifestyle affect a person’s health. Health according to the World Health Organization (WHO) is “a state of complete physical, mental, and social wellbeing and not merely the absence of disease or infirmity”. The specifics of a healthy lifestyle may vary from person to person. Generally, it will include a balance diet, physical exercise, time for family and important relationships, hobbies and downtimes, vacations and a good quality sleep. All of these must harmoniously exist to generate a sense of contentment and satisfaction.
16.01.2024 Volume 3 Issue 1 View more Download
The study focused on the capacity of indigenous strains of lactic acid bacteria to synthesize branched-chain amino acids, a pivotal factor in determining the formulation of a biopreparation designed for the prevention and treatment of obesity. Notably, within the array of strains examined, L. casei K7/3 demonstrated a remarkable twofold increase in branched-chain amino acid production when cultivated in MRS-bouillon medium. Specifically, there was a significant elevation in leucine content, a deficiency or absence of which in the human body can precipitate a decline in body weight, impede development and growth, and lead to metabolic disturbances.
16.01.2024 Volume 3 Issue 1 View more Download
We discuss the problems of genetic qualitative traits of the cotton G. hirsutum L. The regularities of inheritance and splitting in F2 in 23 variants of joint inheritance of 9 qualitative traits are determined and it is found that within the species G. hirsutum L., the presence of an anthocyanin spot at the base of flower petals is controlled by two non-allelic genes with complete dominance of the presence of an anthocyanin spot and joint inheritance and cleavage in F2 of five variants of the sign "presence - absence" of an anthocyanin spot at the base of the petals of a flower with such signs as the shape of the leaf and bracts. Plant coloration, color of flower petals, "presence - absence" of leafy nectaries are observed both trigenous and tetragenic control. In the functioning of their genes, inter-allelic and non-allelic gene interactions (polymerization) are observed.
15.01.2024 Volume 3 Issue 1 View more Download
The era of primitive society is the longest in the history of mankind. According to Professor Yu. P. Lisitsyn, it lasted hundreds of thousands of children, and the entire history of civilization in comparison is no more than one percent. The history of medicine (and pharmacy E. Elyashevich), starting with the first signs of civilization, the transition from the primitive communal to the slave system, and the formation of cities, dates back only a few thousand years. The state of pharmacy of this period was studied using archaeological methods: during excavations of burials, medicines and labor items were found, which may have been used for grinding medicinal herbs and minerals) objects of art
15.01.2024 Volume 3 Issue 1 View more Download
Based on the results of a study of the acute toxicity of a mesh implant with a composite coating, the authors came to the conclusion that a mesh implant with a new composite coating can be classified as a low-toxic drug with a single injection. Based on the fact that a single injection of a mesh implant into the abdominal cavity didn`t cause death in animals, according to the currently accepted WHO classification, the toxicity of this composite coating can be classified as mild.
11.01.2024 Volume 3 Issue 1 View more Download
The paper presents data on the study of the content of cytokines (IL-1β, RAIL-1β, IL-2, IL-4, IL-10, IL-17A, TNF-α, IFN-γ) in morning urine using enzyme immunoassay in healthy individuals (n=20) and in patients with acute glomerulonephritis (n=93). Determination of cytokine levels in patients was carried out at the onset of the disease and 12 months after the manifestation of the disease. The obtained indicators of cytokine content in urine are presented as absolute values in pg/ml and values normalized to creatinine, calculated using the formula: cytokine level (pg/ml) / urine creatinine (µmol/ml). A study was made of changes in the content of cytokines in urine during glomerulonephritis relative to a group of healthy individuals, as well as the dynamics of cytokine content in urine over a 12-month observation period. The results of the study showed that absolute values of cytokines in urine can distort the true picture of the cytokine profile of urine in kidney pathology. Normalized values of the predominant number of pro- and anti-inflammatory cytokines (IL-1β, IL-2, IL-8, IL-10, IL-17A and TNF-α) in patients with glomerulonephritis were significantly higher than the corresponding indicators in healthy individuals. Normalized cytokine values were shown to be more sensitive indicators than absolute values when analyzing differences in the cytokine profile in patients with glomerulonephritis depending on the acute and chronic course of the disease. These indicators influenced the outcome of glomerulonephritis, assessed, as a rule, 12 months after the manifestation of the disease. Thus, low levels of IL-1β, IL-8 and IL-17A found at the onset of the disease in combination with a high level of RAIL-1β determined the chronicity of glomerulonephritis. So, values of cytokine content in urine normalized by creatinine expand the possibilities of using assessment of the cytokine profile of urine to establish changes in the content of cytokines in urine in kidney pathology and predict the nature of the clinical course of glomerulonephritis.
11.01.2024 Volume 3 Issue 1 View more Download
The article presents the results of experimental and morphological studies aimed at solving the issue of treating the cavity of an echinococcal cyst with various antiseptics and assessing the effectiveness of laser radiation. Experiments performed in the laboratory of Republican specialized scientific and practical medical center for surgery named after V.Vakhidov. The main objective of the experimental study was to evaluate the effect of laser exposure in combination with treatment with various antiseptics on the germinal elements of echinococcal fluid and the fibrous layer of the capsule of parasitic cysts. For this purpose, the study is divided into 2 large series. Each series was carried out sequentially. In the first series, the authors gave a macroscopic (visual) and microscopic assessment of each sample
11.01.2024 Volume 3 Issue 1 View more Download
The article presents the results of experimental and morphological studies aimed at solving the issue of treating the cavity of an hydatid cyst with various antiseptics, and assessing the effectiveness of laser radiation. The main objective of the experimental study was to evaluate the effect of laser exposure in combination with treatment with various antiseptics on the germinal elements of echinococcal fluid and the fibrous layer of the capsule of parasitic cysts
11.01.2024 Volume 3 Issue 1 View more Download
This article presents observations of ocular surface clinical condition in patients with primary open-angle glaucoma who had been receiving antihypertensive drugs containing preservatives over an extended period. The study comprises a total of 74 eyes, with patients categorized into three groups. The initial group consists of individuals who had been on a long-term regimen (up to 18 years) of antihypertensive medication containing benzalkonium as a preservative. The second group encompasses 12 patients (24 eyes) who were administered prostaglandin drugs via disposable dropper tubes, devoid of preservatives. The treatment duration for this group ranged from 2 to 2.5 years. Lastly, the third group comprised individuals exhibiting symptoms of conjunctivitis, chosen for the diagnosis of dry eye syndrome based on their subjective complaints. This group includes 10 patients, totaling 20 eyes. Upon analysis, approximately 40% of patients in the main group exhibited symptoms indicative of dry eyes. In the control group that received the preservative-free drug, the occurrence of dry eye symptoms was notably lower at 16.6%, while in the other control group, this frequency stood at approximately 30%. Consequently, the group consistently receiving drugs with a preservative showed a slightly higher percentage in the detection of dry eye
11.01.2024 Volume 3 Issue 1 View more Download
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