A NEW METHOD OF TREATING PATIENTS WITH ACUTE CHOLEDOCHOLITHIASIS Abstract: The results of examination and treatment of 160 patients with acute calculous cholecystitis complicated by choledocholithiasis treated in the department of general surgery of the Central Hospital of the Ministry of Internal Affairs of the Republic of Uzbekistan were analyzed. The aim of the study was to improve the results of treatment of patients with acute calculous cholecystitis complicated by choledocholithiasis by using minimally invasive methods of treatment with nitroglycerin and EAP. At treatment of patients with cholecystitis complicated by choledocholithiasis the use of nitroglycerin and retrograde sanation and lavage of choledochus with EAP-A solution improves the results of treatment and reduces the period of hospital treatment of this category of patients from 12.6 to 8.4 days. All this allows to widely recommend the proposed method of treatment in clinical practice, has economic efficiency.

THE COURSE OF PREGNANCY IN WOMEN WITH BRUCELLOSIS Abstract: Brucellosis is an infection caused by bacteria of the genus Brucella. A person can get sick if they drink unpasteurized milk, eat poorly fried meat, or simply pet an infected animal. At an early stage, brucellosis is easy to cure, without treatment, the disease leads to the destruction of internal organs. Brucellosis (Bang's disease, Maltese fever, Gibraltar fever, Cyprus fever, undulating fever) is an acute bacterial infection that is transmitted to humans from infected animals.

RISK OF FETAL GROWTH RESTRICTION SYNDROME IN WOMEN WITH BLEEDING EARLY GESTATION Abstract: The article provides an overview of scientific research concerning the problem of the risks of low birth weight children, including those with fetal growth restriction syndrome. The reasons for the development of fetal growth restriction syndrome and the possibility of predicting it in women with bleeding in early pregnancy are considered to improve perinatal outcomes.

SOME ASPECTS OF THE ROLE OF HUMAN PAPILLOMAVIRUS INFECTION IN THE DEVELOPMENT OF CERVICAL DYSPLASIA Abstract: The detection of HPV infection during a preventive examination of healthy women and patients with dysplastic changes in the cervical mucosa is still at the outpatient stage, and adequate antiviral therapy in these women can serve as an effective pathogenetic prevention of precancerous and tumor diseases of the cervix uteri According to the results of the study. Treatment regimens have been developed and implemented in patients with identified HPV infection with a constant cervix, as well as in the presence of background and precancerous diseases of the cervix.

SOME ASPECTS OF THE PATHOGENESIS OF ALLERGIES IN HYPERTENSIVE PREGNANCY SYNDROME Abstract: In the pathogenesis of cell damage in hypertensive conditions of pregnant women, there are significant allergic reactions and anaphylactic cytotoxicity. Two variants of allergy have been established for hypertension of pregnant women: a clear clinical picture of allergy; latent (latent) sensitization. It was revealed that with hypertension of pregnant women, allergic diseases are more common in repeatedly and multiparous women. It has been determined that with a combination of allergy and hypertension, a more severe clinical course is more often observed. improving the quality of early diagnosis, treatment and prevention.

KIDNEY CYSTS IN CHILDREN Abstract: Cysts in childhood are a common occurrence. Among them there are quite a large group consists of sporadic cases, as well as random detection of single cysts in the kidney during routine ultrasound; the cause of the appearance of such cysts remains the subject of research. Modern genetics has made a great contribution to the differentiation of various kidney cysts. Polycystic kidney disease is a hereditary nephropathy associated with a mutation of genes that determine the structure of the renal tubules in their embryonic development, manifested by the formation of cysts in the renal parenchyma, an increase in which leads to sclerosis of the kidney tissue and the development of chronic renal failure.

ON THE ETYMOLOGY OF THE ETHNONAME “UYGUR” Abstract: World scientists recognize that the Uyghurs are one of the oldest among the Turkic peoples and played an important role in the history of world civilization, Central Asia, in particular, the Great Silk Road. For this reason, the history of the Uyghurs has been and continues to be the focus of attention of many scholars.

THE KAOLIN RAW MATERIAL BASE OF UZBEKISTAN AND THE PROSPECTS FOR ITS USE Abstract: Kaolin is a claey sedimentary rock consisting of kaolinite and associated mainly with weathering crusts. Kaolin is widely used in the paper, ceramics, refractory, paint, rubber, cable, cosmetic and pharmaceutical industries. In addition, one of its modern directions is aluminum mining. The main large deposits of the world are located in Ukraine, the Czech Republic, and Great Britain and belong to the type of hydrothermal deposits. Primary and secondary kaolins from the Angren deposit are part of the raw material base of our republic.

A TEACHER WHO SPEAKS WISE WORDS Abstract: This article is devoted to the topic of reading Hamid Olimjon's works for children. In particular, we are talking about fairy tales. Folktales are usually rooted in folklore. Hamid Olimjon's fairy tales are written in poetic, fluent language and are distinguished by their unique and interesting plots. Fairy tales, especially their poetic forms, play an important role in the formation of children's imaginations and thoughts. Expands worldview, increases creative abilities.

ANALYSIS OF THE POSSIBILITY OF VENTURE, INNOVATION AND OTHER TYPES OF INVESTMENT IN SCIENTIFIC RESEARCH AND DEVELOPMENT Abstract: The article analyzes the possibility of venture, innovative and other types of investment in scientific research and development, taking into account the risks and long period of return, and offers recommendations for their improvement