The article deals with the history of the emergence of wool as a subject of entrepreneurship in England. The advantage and peculiarities of the development of this business in the origins of entrepreneurship, gaining world fame and becoming international are defined.
01.05.2024 Volume 3 Issue 4 View more Download
In this work, the growth and development of cotton plants by day was studied for the first time. Exposure to UV rays was discovered to accelerate the growth and development of cotton variety “Tashkent - 6”. With ultraviolet (UV) irradiation, the appearance of fetal elements increases. UV irradiation of cotton bushes leads to an increase in yield up to 55-60%.
01.05.2024 Volume 3 Issue 4 View more Download
Fever plays an important role in fighting infections, and although it can be inconvenient, it does not require treatment in a child who does not have other diseases. Some studies even show that lowering the temperature can prolong some diseases. However, fever increases the metabolic rate and the load on the cardiopulmonary system. Thus, fever can be harmful to children with pulmonary or cardiac risks or neurological disorders. It can also be a catalyst for febrile seizures, which, as a rule, although benign, cause very great concern among parents and should also be differentiated from more serious diseases (for example, meningitis). In children, the ability to regulate the thermal balance of the body is relatively weak, so it is easier for them to overheat or hypothermia of the body than in adults. The main reason for this is the insufficient development of the nervous mechanisms of regulation of thermal balance and, first of all, vascular reactions. Premature infants are unable to maintain their temperature homeostasis and react to ambient temperature as poikilothermic.
30.04.2024 Volume 3 Issue 4 View more Download
Liver diseases, the symptoms of which are expressed in constant nausea, heartburn, an unpleasant odor from the oral cavity, and a yellowish skin color have become more and more frequently diagnosed in the last decade. Many people know about liver diseases today. The main, most common are cirrhosis, hepatitis, and cholecystitis. Liver treatment will depend on the disease, its stage, and the individual characteristics of the course.
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Ammonia is a key metabolite derived from amino acid metabolism and breakdown of nitrogenous substances in the gut,1,2 and present hypotheses suggest that it is of central importance in the pathogenesis of hepatic encephalopathy. Current therapeutic strategies are directed towards reducing circulating concentrations of ammonia. The two main pathways of ammonia detoxification are synthesis of urea and glutamine. In the physiological state, the liver is central in urea synthesis and this forms the basis of ammonia removal.3 The other organs capable of metabolising ammonia are the brain and skeletal muscle through synthesis of glutamine. In the presence of liver disease however, loss of functional liver mass and portocaval shunting may contribute to increased ammonia levels in plasma, thus predisposing to hepatic encephalopathy. In cirrhotic patients, skeletal muscles play an important role in the detoxification of ammonia to glutamine.4 Glutamine synthesis is however only a temporary method of ammonia detoxification. To remove ammonia from the body in a situation when urea synthesis is compromised (as happens in liver disease) requires transport of glutamine to the kidney, where it is metabolised to release ammonia, which is then excreted in urine.
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The method is based on the detection of even small concentrations of the desired diagnostic element. To determine the initially extremely small concentrations of RNA or DNA that need to be determined during the main stage of the study, a method is used to artificially increase the amount of RNA or DNA.
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Creatine phosphate is a reserve of explosive energy. Creatine is a substance of skeletal muscles, myocardium, and nervous tissue. In the form of creatine phosphate, creatine is a “depot” of macroergic bonds and is used for rapid resynthesis of ATP during cell work. Creatine phosphate was first isolated from muscle tissue in 1927 [1]. However, the study of its role and influence on various processes in the human body continues to this day. This is explained by the fact that creatine phosphate is an energy substrate for the rapid synthesis of ATP under anaerobic conditions. That is, the formation of ATP does not require oxygen and the participation of mitochondria. In turn, ATP is a universal source of energy in the human body.
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Iron is a vital trace element. Iron is part of the hemoglobin of erythrocytes (red blood cells) and carries oxygen from the lungs to the tissues. Iron is necessary for every cell of the body, as it contributes to the process of its respiration. Iron is part of enzymes, ensuring their normal functioning and metabolic reactions. Adult men and women require only 8 mg/day. Women of childbearing age require a dose of 18 mg/day; during pregnancy, the need increases to 27 mg/day.
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The coronavirus disease 2019 (COVID-19) epidemic is a public health emergency of international concern. During the initial phase of the COVID-19 outbreak in China, more than half of respondents rated the psychological impact as moderately severe, and about one third reported moderate to severe anxiety. In this regard, in addition to physiotherapeutic measures and exercise therapy, the complex of rehabilitation measures necessarily includes educational programs for training patients with the aim of their psychosocial adaptation.
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This study addresses the issue of the spread of synthetic cathinones, specifically Alpha-PVP, and their impact on public health. The paper thoroughly describes the chemical composition, metabolism, pharmacological, and toxicological aspects of synthetic cathinones. Issues of regulation and control over the distribution of these substances are discussed, as well as the role of the internet in their sale. The authors emphasize the need for further research to develop effective methods for prevention and treatment of dependencies caused by these dangerous substances.
30.04.2024 Volume 3 Issue 4 View more Download
SCIENCE & INNOVATION