Hemoglobinopathies are a group of severe hereditary blood diseases caused by a violation of the structure of hemoglobin or a decrease in the synthesis of one or more globin chains. The clinical picture is extremely varied. Common symptoms are hemolytic anemia, enlarged spleen, and bone damage. Diagnosis is carried out using peripheral blood smear microscopy, hemoglobin electrophoresis, and genetic studies. For treatment, transfusions of blood components, hydroxyurea preparations, and infusion therapy are used. In severe patients, splenectomy and stem cell allotransplantation are performed.
04.05.2024 Volume 3 Issue 4 View more Download
This article analyzed literary information about the features of the development of neurological disorders in cystic fibrosis (CF), about modern views on the early diagnosis of this pathology. A generalized analysis of scientific foreign and domestic literature shows that this problem still has a number of complex unresolved issues. Integrating mental health screening, early detection of neurological disorders, and targeted treatment of patients with CF may reduce the mortality and disability observed in this disease.
03.05.2024 Volume 3 Issue 4 View more Download
According to most researchers, today there is a tendency to increase the incidence of many allergic pathologies, including such pathologies as bronchial asthma (BA), in addition, most patients with this pathology have the addition of combined diseases, among which allergic rhinitis is most often diagnosed as a concomitant pathology in BA. The purpose of this study was to evaluate comorbid forms of asthma in combination with allergic rhinitis in children. The study was based on a survey of 42 children diagnosed with atopic asthma, during which, according to the results of an ENT examination, it was revealed that allergic rhinitis was diagnosed in 23 (54.8±4%) of the studied children
03.05.2024 Volume 3 Issue 4 View more Download
This article discusses the provision of clean drinking water, the composition of open and groundwater, the impact of unfit for human health on human health, the diseases caused by them, drinking water treatment standards and treatment processes referred to.
03.05.2024 Volume 3 Issue 4 View more Download
The nosology of acute poisoning is extremely diverse and differs significantly in different countries. In Uzbekistan, the bulk of poisoning is accounted for by alcohol and its surrogates, acids (mainly acetic) and alkalis, various medications, mainly hypnotics and sedatives, organophosphorus and other pesticides. The biological activity of chemical compounds is determined by their structure, physical and chemical properties, dose (concentration) and duration of exposure; features of intake and biotransformation in the body; resistance of tissues and organs to poisons and the individual characteristics of a particular victim. In this regard, the forensic medical assessment of concomitant acute poisoning is a very relevant and unresolved problem.
01.05.2024 Volume 3 Issue 4 View more Download
In this article, the author presents the results of studies assessing the effect of vaccination against Streptococcus pneumoniae on the incidence of respiratory diseases in children, in addition, data from the author’s own studies of pneumococcus in young children. 495 sick children of early and older age with acute respiratory infections who were under observation at the TashPMI clinic and the city children were examined in hospital number 1 of Tashkent.
01.05.2024 Volume 3 Issue 4 View more Download
Analysis of the range of medicines used for urinary tract infections registered in the Republic of Uzbekistan showed that on the pharmaceutical market of Uzbekistan they are presented in such dosage forms as oral solutions, injection solutions, capsules and tablets. The number of registered medicines in the State Register for 2022 was 80 items. Content analysis was used as a methodology. The main objective of the ongoing pharmaceutical market research is to determine the share of domestic manufacturers in connection with the adoption by government authorities of appropriate measures for the development of domestic pharmaceutical manufacturers
01.05.2024 Volume 3 Issue 4 View more Download
Bruising or bleeding after injury is a common occurrence. But some people have disorders that result in bruising or bleeding too often. Sometimes people start bleeding for no apparent reason or injury. Establishing the patient's condition with bruising from various factors is important for rapid treatment and prevention of complications. And it is of great importance in forensic medical examinations.
01.05.2024 Volume 3 Issue 4 View more Download
This article examines the current trends and prospects for dental services in Uzbekistan, shedding light on the evolving landscape of oral healthcare in the country. With a growing focus on healthcare infrastructure and advancements in dental technology, Uzbekistan's dental services sector is undergoing significant transformation. The article explores key trends such as the expansion of dental clinics, increased access to specialized care, and a rising emphasis on preventive dentistry. It also discusses the challenges and opportunities that lie ahead, including the importance of dental education and the potential for international collaboration
01.05.2024 Volume 3 Issue 4 View more Download
Various brain structures, their interaction and, consequently, mental functions reach full development at different ages and in a specific way determine the individual characteristics of the child. When the rates of development of functional systems differ, developmental heterochronies arise. Heterochrony is manifested by the uneven development of functional systems, which must meet the need to comply with the changing forms of interaction of the child with the environment. However, it is argued that heterochronies in the development of functional systems can become the basis for partial delays in motor, speech or mental development. In connection with the above, in this article the authors studied EEG signs that allow us to judge the level and degree of irritation of the brain stem structures under mental stress in primary school students against the background of long-term adaptation to intellectual stress associated with classes in the chess universal education program, which is relevant .
01.05.2024 Volume 3 Issue 4 View more Download
SCIENCE & INNOVATION