PREDICTING THE CONSEQUENCES OF CLINICAL, IMMUNOLOGICAL AND IMMUNOCHEMICAL RESULTS OF RELATED KIDNEY TRANSPLANTATION

Bakhritdinov F.Sh.; Matkarimov Z.T.; Komilova D.N.; Elmurodova N.B.

doi:10.5281/zenodo.12534672

Bakhritdinov F.Sh., Matkarimov Z.T., Komilova D.N., Elmurodova N.B.

Abstract. The article describes the effectiveness of the acetylation phenotype in clinical use, taking into account the identified relationships between the acetylator status of the donor and recipient, and graft function, the risk of rejection and the choice of immunosuppressive protocol, in terms of predicting the results of related kidney transplantation. The developed method for predicting possible complications after KT taking into account the acetylation phenotype, CYP3A5 genotype and glomerular filtration rate allowed us to classify the risk as low, medium or high.

Keywords: genotypic HLA typing, Cross-Match tests, acetylation phenotype

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