COMPARATIVE ANALYSIS AND DYNAMICS OF ECHOCG PARAMETERS IN PATIENTS WITH IHD AND T2DM WITH DIFFERENT CATEGORIES OF LVEF AT THE STAGES OF OBSERVATION

20.06.2024 International Scientific Journal "Science and Innovation". Series D. Volume 3 Issue 6

Sh.Sh. Mukhtarova, R.Kh. Trigulova, Kh.K. Nasirova, D.A. Alimova

Abstract. This article is devoted to assessing the relationships between EchoCG parameters and their dynamics in the ranges of preserved and moderately reduced LVEF in patients with coronary artery disease and type 2 diabetes. We examined 130 patients with type 2 diabetes and coronary artery disease with varying LVEF at the age of 65.6±9.7 years with an experience of 8.8±5.2 and 7.5±3.6 years, respectively. The results of the LVDP value between groups 2 and 3 at the outcome differed in the E/e` indicator (t==7.02, p=0.008), due to the E parameter (t==6.011, and p=0.01). At the observation stages, positive dynamics were recorded on the part of E/A in groups 2 (t==6.727, p=0.009) and 3 (t==15.830, p=0.000), E/e' (t==7.422, p=0.006 ) and (t==17.775, p=0.000) respectively. Conclusion: the identified main indicators of LVDD respond to therapy with Empagliflozin with a fairly high statistically significant power.

Keywords: diabetes mellitus type 2; cardiac ischemia; heart failure; ejection fraction; left ventricular diastolic dysfunction.