Abstract. Frequency, structure and clinical displays Purulent flammatory diseases at 112 children at the age from 0 till 15 years were on treatment in branch of the second Tashkent children’s surgical hospital and addressed for out-patient the help in a polyclinic are studied. Now a number of aspects Pyoinflammatory diseases at children's age requires revision owing to the changed mutual relations between the microbic activator and an organism of the child. Researches testify to change of specific structure of activators Pyoinflammatory diseases in children's age. It is necessary to underline, that absence is connected with plurality of factors of pathogenicity nosologic the specificity, infections caused by is conditional-pathogenic microorganisms that distinguishes them from the majority of pathogenic bacteria. As a rule, standard treatment for most purulent-inflammatory diseases of the musculoskeletal system involves surgical intervention followed by the application of antibacterial and symptomatic therapy. However, correction of immune-metabolic disorders using medications and physiotherapeutic methods is not always employed.The authors also claim that the treatment of this group of patients should be based on a comprehensive approach involving both surgical interventions and therapeutic measures. Surgical methods for treating purulent-inflammatory diseases of the musculoskeletal system dominate and consist of the following main components: primary or secondary surgical treatment of the purulent focus (with removal of the causative tooth of odontogenic origin if applicable) during adequate wound drainage. Special attention is paid to the surgical approach, which should provide the shortest possible route to the purulent focus while also creating adequate conditions for exudate evacuation without forming sinuses and pockets. The therapeutic regimen is divided into general measures, including antibacterial, desensitizing, immunostimulating, detoxifying, and other treatment methods, and local treatment, which involves ensuring adequate drainage of purulent exudate from the focus of inflammation, suppression of the activity of pathogenic microorganisms, maintenance of tissue necrosis, reduction of interstitial pressure, normalization of microcirculation, and acceleration of regeneration processes. It should be noted that currently, most researchers and clinicians adhere to the concept of therapeutic measures that take into account the stages of the purulent-inflammatory process and the pathophysiological processes occurring in the purulent focus.