Abstract. More than 20 strains of persistent cultures of microorganisms were isolated from the soil of a former pesticide warehouse in the Mirzabad district of the Syrdarya region. The prevailing concentrations were distinguished by 3 -bacterial cultures: Bacillus megaterium, Bacillus subtilus, Pseudomonas aeruginosa and 2 -actinomycete cultures: Streptomyces violaceorubidus, Streptomyces rochae. The isolated cultures were resistant to high salt concentrations, such as NaCl and Na2SO4. It was found that at concentrations of 10-15%, added to the nutrient medium of NaCl and Na2SO4 salts, the selected cultures had the ability to grow with the formation of a sufficient concentration of biomass in the culture medium
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