Abstract. Postpartum depression (PPD) is a serious mental health condition that affects 10-15% of women after childbirth. PPD has negative consequences for maternal wellbeing, child development, and family functioning if not treated. This literature review examines evidence-based methods for preventing PPD, focusing on pharmacological interventions, psychological interventions, social support, and alternative approaches. Overall, psychological and social support interventions demonstrate the strongest evidence for PPD prevention. Effective psychological approaches include interpersonal psychotherapy, cognitive behavioral therapy, and mindfulness training before and after birth. Social support from partners, community workers, and peers also help lower PPD risk. Promising alternative interventions require further research but include exercise, infant massage, and dietary supplements. Additional investigations should prioritize accessible, cost-effective prevention programming among high-risk populations. Ultimately, a tailored, multilevel approach across the perinatal period shows the greatest promise to reduce the burden of PPD.
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