APPLICATION OF THE BETHESDA CLASSIFICATION IN THE HISTOPATHOLOGICAL CHARACTERISTICS OF PATIENTS WITH THYROID NODULES

20.02.2024 International Scientific Journal "Science and Innovation". Series D. Volume 3 Issue 2

Dadakhanova Maryam Bakhtiyarovna, Khalimova Zamira Yusufovna

Abstract. Background. The Bethesda Classification for Reporting Thyroid Cytopathology (BSRTC) was developed in 2010 to provide a standardized framework for interpreting and reporting FNA cytology, and its use is recommended for the evaluation of thyroid nodules in both adults and children. Material and methods. A retrospective analysis of 51 patients with thyroid nodules was performed. Of the 51 patients, 33 were men and 18 were women. Research methods - general clinical, biochemical (bilirubin, direct, indirect, ALT, AST, PTI, coagulogram, CRP), hormonal (TSH, free thyroxine, antibodies to thyroid peroxidase, to thyroglobulin and thyrocyte receptors, prolactin in the blood) and instrumental: ECG, Ultrasound of the thyroid gland, internal organs, chest x-ray, as well as fine-needle aspiration biopsy (FNA). Research results. The patients were divided into 2 groups: group 1 - patients with one nodular thyroid formation - 35 patients, group 2 - patients with multinodular thyroid formations - 16 patients. 20 healthy individuals made up the control group. Conclusions.1) The majority of patients, a total of 22 out of 51 patients, belonged to Bethesda category II (43.1%), while 2 - category I (3.9%), 6 - category III (11.8%), 12 - category IV (23.5%), 7 - category V (13.7%) and 2 patients belonged to category VI (3.9%) respectively. 2 patients with Bethesda category I underwent repeat FNA, and later they had category II. 2) When analyzing the cytological response, the Bethesda classification must be used for correct prognosis and treatment.

Keywords: thyroid gland, nodules, formations