VIRTUAL PHANTOM DOSE CALCULATIONS IN PROTON THERAPY USING GEANT4

Saidova S.; Mamayusupova M.; Abdukholikov F.; Ashurov S.

doi:10.5281/zenodo.10491857

VIRTUAL PHANTOM DOSE CALCULATIONS IN PROTON THERAPY USING GEANT4

11.01.2024 International Scientific Journal "Science and Innovation". Series A. Volume 3 Issue 1

Saidova S., Mamayusupova M., Abdukholikov F., Ashurov S.

Abstract. This paper explores the application of GEANT4, a Monte Carlo simulation toolkit, for dose calculations in virtual phantoms within the context of proton therapy. The study aims to provide a comprehensive comparison of the simulated dose data obtained from GEANT4 with existing data available on OpenDose.org. The virtual phantom serves as a crucial tool in replicating the intricacies of human anatomy for accurate proton therapy simulations. The Monte Carlo simulations consider various proton interactions, including elastic and inelastic scattering, bremsstrahlung, and ionization. The article discusses the significance of GEANT4 in capturing the complex physics of proton interactions and explores the potential implications for treatment planning and optimization.

Keywords: Virtual phantom, Dose calculations, GEANT4, OpenDose.org, Monte Carlo simulations, Proton therapy, Treatment planning, Relative Biological Effectiveness (RBE), Ionization, Bragg peak, CT data integration, Accelerated Monte Carlo, Graphical processing units (GPUs), Elastic and inelastic scattering, Bremsstrahlung, Dual-energy CT scanners, Treatment effectiveness, Solid tumor treatment, Biological response, Optimization strategies, Research and development, Clinical outcomes, Proton interactions,

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