COMPARATIVE ASSESSMENT OF HEPATOPRO-TECTIVE ACTIVITY OF BRASSICA RAPA, NIGELLA SATIVA, SAMBUCUS NIGRA SUBSTANCES WITH C-4 AND PHOSPHOGLIV PREPARATIONS

Abdugafurova D.G.; Mahmudov L.U.; Аmanlikova D.A.; Oripova M.J., Qoraboyeva B.B., Qo’ziyeva Z.N., Oshchepkova Yu.I.

doi:10.5281/zenodo.10395952

Abdugafurova D.G., Mahmudov L.U., Аmanlikova D.A., Oripova M.J., Qoraboyeva B.B., Qo’ziyeva Z.N., Oshchepkova Yu.I.

Abstract. A comparative study of the hepatoprotective activity of the substances Brassica rapa, Nigella sativa, Sambúcus nígra with comparison drugs C-4 and Phosphogliv in acute hepatitis induced by carbon tetrachloride (CCl4) was carried out in experiments. The results of a comparative assessment of the hepatoprotective activity of Brassica rapa, Nigella sativa, Sambúcus nígra substances with C-4 and Phosphogliv preparations showed a high degree of hepatoprotective properties of Brassica rapa substances at a dose of 20 mg/kg and Sambúcus nígra at a dose of 30 mg/kg, which in the future can be used to create a biologically active additive (dietary supplement) for treatment of diseases of the hepatobiliary system

Keywords: substances of medicinal plants, hepatoprotector, hepatitis, carbon tetrachloride, liver, peripheral blood

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