Abstract. The article is about the life and work of Mominjon Hakim Margilani, medical activity, socio-political processes in the Khanate of Bukhara and Kokan Khanate in the early 20th century, education, theory and practice of medicine, exemplary aspects of the personality of Mominjon Hakim, Turkestan medicine, public health, population's attitude towards scientists. dedicated to the analysis of unique facts, the achievements of Mominjon Hakim in combining the advanced aspects of Eastern medicine and Western medicine, and the unique aspects of his unique personality.