ASSOCIATION OF DOPAMINERGIC RECEPTORS OF PERIPHERAL BLOOD LYMPHOCYTES WITH A RISK OF DEVELOPING ANTIPSYCHOTIC EXTRAPYRAMIDAL DISEASES

Antsiborov Sergey Vadimovich; Turayev Bobir Temirpulotovich; Sharapova Dilfuza  Nematillayevna; Shernazarov Farrukh

doi:10.5281/zenodo.10103964

ASSOCIATION OF DOPAMINERGIC RECEPTORS OF PERIPHERAL BLOOD LYMPHOCYTES WITH A RISK OF DEVELOPING ANTIPSYCHOTIC EXTRAPYRAMIDAL DISEASES

10.11.2023 International Scientific Journal "Science and Innovation". Series D. Volume 2 Issue 11

Antsiborov Sergey Vadimovich, Turayev Bobir Temirpulotovich, Sharapova Dilfuza Nematillayevna, Shernazarov Farrukh

Abstract. The pathophysiological mechanisms behind the development of schizophrenia spectrum disorder remain an unknown and little-studied problem to date. The discovery of antagonistic mechanisms of action on dopamine receptors, through which the emergence of antipsychotic effects led to the formation and subsequent development of schizophrenia dopamine theory, which raised reasonable hope within the professional community that pharmacological drugs that reduce dopaminergic neurotransmission would be a "golden blow" in the treatment of schizophrenia spectrum disorders

Keywords: dopaminergic receptors, antipsychotic effects, dopamine theory schizophrenia

References:

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