WHETHER EXIST LINKS BETWEENTOXIC LIVER INJURY AND RISK OF POSTMASTECTOMIC LYMPHEDEMA IN BREAST CANCER PATIENTS?

01.11.2023 International Scientific Journal "Science and Innovation". Series D. Volume 2 Issue 10

Djurayev Mirjalol Dekhanovich, Uzokov Sokhib Makhsudovich, Kutlumuratov Atabek Bekchanovich, Esankulova Bustonoy Sobirovna

Abstract. The link between risk of development at breast cancer patients (BCP) the secondary postmastectomic lymphedema (SL) on the one hand and signs which are accompanying vascular pathology (AVP), chronic gynecologic diseases (CGD) and toxic liver injury (TLI) with another hand to the moment of surgical intervention is investigated according to clinical supervision and electrocardiographic and ultrasonic researches. The link between sings of AVP and of TLI was not detected(p>0.05). However, we observed the link between TLI and CGD(p<0.05), but especially it was appreciable for ultrasonic signs of TLI(p<0.05). Radical mastectomy (RME) and one-stage imposing of lymphatic-venous anastomosis effectively prevented SL during five years' of supervision, including patients with presence at them ultrasonic signs of TLI(p<0.05). These findings are supposing prognostic value of ultrasonic investigation of patients before standard RME from the point of view of risk SL during five years' after operation.

Keywords: radical mastectomy, surgical, breast cancer, postmastectomic lymphedema