PRECANCER CERVICAL DISEASES AND PREGNANCY

Ruzieva Nodira Khakimovna; Zhuraeva Nilufar Abdulla kizi

doi:10.5281/zenodo.10059136

PRECANCER CERVICAL DISEASES AND PREGNANCY

31.10.2023 International Scientific Journal "Science and Innovation". Series D. Volume 2 Issue 10

Ruzieva Nodira Khakimovna, Zhuraeva Nilufar Abdulla kizi

Abstract. The purpose of the review: to summarize the current knowledge on the diagnosis and treatment of precancer of the cervix during pregnancy. The article presents a review of the literature on epidemiology, classification, developmental risk factors, symptoms and diagnosis, principles of treatment of precancerous diseases of the cervix, management of pregnant women with this pathology

Keywords: precancer and cervical cancer, etiology, risk factors, pregnancy, principles of management.

References:

1. Атабиева А.Д., Пикуза Т.В., Чилова РА., Жукова Э.В, Трифонова Н.С. Заболевания шейки матки при беременности и современные методы их диагностики (обзор литературы) / Вестник современной клинической медицины. — 2016. — Т. 9, вып. 4. — С.72—83 DOI: 10.20969/VSKM.2016.9(4).72-83. 2. Бебнева Т. Н., Радзинский В. Е., Костин И. Н., Покуль Л. В. Тактика ведения беременных женщин с предраковыми процессами шейки матки //Доктор.Ру. 2017. № 9 (138). С. 33–37. 3. Ершов В.А., Лисянская А.С., Ронжина Е.А., Рахминова Е.Р. Значение белков L1 вируса папилломы человека и NuMA1 в прогнозе цервикальной интраэпителиальной неоплазии, ассоциированной с ирусом папилломы человека высокого канцерогенного риска.// Акушерство и гинекология: Научно-практический журнал. 2017. № 11. - С. 63 68. 4. Злокачественные новообразования в России в 2016 году (заболеваемость и смертность) / Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. – М.: МНИОИ им. П.А. Герцена - филиал ФГБУ “НМИРЦ” Минздрава России, 2018. – 250 с. 5. Состояние онкологической помощи населению России в 2015 году / Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. – М.: МНИОИ им. П.А.Герцена - филиал ФГБУ “НМИРЦ” Минздрава России, 2016 – 236 с. 6. Состояние онкологической помощи населению России в 2016 году / Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. – М.: МНИОИ им. П.А.Герцена - филиал ФГБУ “НМИРЦ” Минздрава России, 2017 – 236 с. 7. Трубникова Л.И., Вознесенская Н.В., Таджиева В.Д.,КорниловаТ.Ю., М.Л., Тихонова Н.Ю. Учебно- методическое пособие. Актуальные вопросы гинекологии. Ульяновск, 2019.266с./Под редакцией проф. Л.И. Трубниковой. 8. Урманчеева А. Ф. Гинекологический рак в сочетании с беременностью. Практ. онкология. 2009; 10(4): 184–97. 9. Урманчеева А.Ф. Опухоли женских половых органов и беременность. Пособие для врачей / А.Ф. Урманчеева, Е.А. Ульрих – СПб.: Изд-во Н-Л, 2011. –40 с. 10. Чиссов В. И., Старинский В. В., Петрова Г. В. Состояние онкологической помощи населению России в 2010 г. М.: ФГХ «МНИОИ им. П. А. Герцена»; 2011: 188. 11. ACOG. American College of Obstetricians and Gynecologists. Cervical Cancer. Available at: http://www.acog.org/Patients/FAQs/Cervical-Cancer. 7/2014. Last accessed 9/28/2014. 12. A.D.A.M.Cervical Dysplasia.2014. Available at: http://www.ncbi.nlm.nih.gov /pubmedhealth/PMH0002461/. Last accessed on October 29, 2014 13. Al-Halal, H. Incidence and obstetrical outcomes of cervical intraepithelial neoplasia and cervical cancer in pregnancy: a population-based study on 8.8 million births / H. Al-Halal, A. Kezouh, H.A. Abenhaim // Arch Gynecol Obstet. – 2013. – Vol. – 287. – № 2. – P. 245 – 250., 14. Booth C. N., Bashleben C., Filomena C. A., Means M. M., Wasserman P. G., Souers R. J. et al. Monitoring and ordering practices for human papillomavirus in cervical cytology: findings from the College of American Pathologists Gynecologic Cytopathology QualityConsensus Conference working group 5. Arch. Pathol. Lab. Med. 2013;137(2): 214–9. 15. College of American Pathologists Gynecologic Cytopathology Quality Consensus Conference working group 5. Arch. Pathol. Lab. Med. 2013;137(2): 214–9. 16. Coppolillo, E.F. High-grade cervical neoplasia during pregnancy:diagnosis, management and postpartum findings / E.F. Coppolillo, H.M. De Ruda Vega, J. Brizuela, M.C. Eliseth // Acta Obstet Gynecol Scand. – 2013. –Vol. 92. – № 3. – P. 293-297. 17. Cubo-Abert M. Risk factors for progression or persistence of squamous intraepithelial lesions diagnosed during pregnancy / M. Cubo-Abert, C. CentenoMediavilla, P. Franco-Zabala // J Low Genit Tract Dis. – 2012. – Vol. 16. – № 1. –P. 34-38 18. Dugué PA, Rebolj M, Garred P, Lynge E. Immunosuppression and risk of cervical cancer. Expert Rev Anticancer Ther. 2013;13(1):29-42. 19. Fleury A. C., Birsner M. L., Fader A. N. Management of the abnormal Papanicolaou smear and colposcopy in pregnancy: an evidencedbased review. Minerva Ginecol. 2012; 64(2): 137–48. 20. Founta C., Arbyn M., Valasoulis G., Kyrgiou M., Tsili A., Martin-Hirsch P.et al. Proportion of excision and cervical healing after large loop excision of the transformation zone for cervical intraepithelial neoplasia. BJOG. 2010; 117(2): 1468–74. 21. Hernández-Hernández D.M., Apresa-García T., Patlán-Pérez R.M. Epidemiological overview of uterine cervical cancer / D.M. Hernández-Hernández, // Rev. Med. Inst. Mex. Seguro. Soc. – 2015. – Vol. 53, Suppl. 2. – S. 154-161. 22. House M. Three-dimensional, extended field-of-view ultrasound method for estimating large strain mechanical properties of the cervix during pregnancy / M.House, H. Feltovich, T.J. Hall [et al.] // Ultrason Imaging. – 2012. – Vol. 34, N. 1. P. 1-14. 23. Hunter M.I. Cervical neoplasia in pregnancy. Part 1: screening and management of preinvasive disease / M.I. Hunter, B.J. Monk, K.S. Tewari // Am J Obstet Gynecol. – 2008. – Vol. 199. – № 1. – P.3-9, 24. IARC. International Agency for Research on Cancer. Chapter 2: An introduction to cervical intraepithelial neoplasia (CIN). Available at: http://screening.iarc.fr/colpochap.php?chap=2. 2014. Last accessed 9/7/2014. 25. Jin G. Pregnancy outcome following loop electrosurgical excision procedure (LEEP) a systematic review and meta-analysis. Arch. Gynecol. Obstet. 2014; 289(1): 85–9 26. Kärrberg, C. Colposcopically directed cervical biopsy during pregnancy; minor surgical and obstetrical complications and high rates of persistence and regression / C. Kärrberg, M. Brännström, B. Strander // Acta Obstet Gynecol Scand. –2013. – Vol. 92. – № 6. – P. 692–699., 27. Khalid S., Dimitriou E., Conroy R., Paraskevaidis E., Kyrgiou M., Harrity C. et al. The theckne LLETZ specimens can predict the relative risk of pregnancy-related morbidity. BJOG. 2012; 119(6):685–91, 28. Kim Y. H., Park J. S., Norwitz E. R., Park J. W., Kim S. M., Lee S. M.et al. Genotypic prevalence of human papillomavirus infection during normal pregnancy: a cross-sectional study. J. Obstet. Gynaecol. Res.2014; 40(1): 200–7 29. Kyrgiou, M. Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions: systematic review and meta-analysis /M. Kyrgiou, G. Koliopoulos, P. Martin-Hirsch, M. Arbyn // Lancet. – 2006. – Vol. 36. –P. 489–98 30. Kyrgiou M., Arbyn M., Martin-Hirsch P., Paraskevaidi S. E. Increased risk of preterm birth after treatment for CIN. Br. Med. J. 2012; 345: e5847 31. Lee JK, So KA, Piyathilake CJ, Kim MK. Mild obesity, physical activity, calorie intake, and the risks of cervical intraepithelial neoplasia and cervical cancer. PLoS One. 2013;12;8(6):e66555. 32. Liu P., Xu L., Sun Y., Wang Z. The prevalence and risk of human papillomavirus infection in pregnant women. Epidemiol. Infect. 2014; 142(8): 1567–78. 33. Massad, L.S., Einstein M.H., Huh W.K Updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. 2012. ASCCP Consensus Guidelines Conference. // J Low Genit Tract Dis. – 2013. – Vol. 5. – № 1. – P.1–27 34. Mitsuhashi, A. Loop electrosurgical excision procedure (LEEP) during first trimester of pregnancy / A. Mitsuhashi, S. Sekiya // Int J Gynaecol Obstet. – 2000. –Vol. 71. – № 3. – P. 22–79. 35. NHS Cervical Screening Programme Colposcopy and Programme Management NHSCSP Publication number 20 Third Edition March 2016 Public Health England leads the NHS Screening Programmes 36. Origoni M., Salvatore S., Perino A., Cucinella G., Candiani M. Cervical intraepithelial neoplasia (CIN) in pregnancy: the state of the art. Eur. Rev. Med. Pharmacol. Sci. 2014; 18(6): 851–60 37. Ortoft, G. After conisation of the cervix, the perinatal mortality as a result of preterm delivery increases in subsequent pregnancy / T. Henriksen, E. Hansen, L. Petersen. BJOG. – 2010. – Vol 117. – 3. –P. 258 – 267 38. Paraskevaidis, E. Management and evolution of cervical intraepithelial neoplasia during pregnancy and postpartum / G. Koliopoulos, S. Kalantaridou, L. Pappa // Eur J Obstet Gynecol Reprod Biol. – 2002. – Vol 104. –1. P. 67-69 39. Roura E, Castellsague X, Pawlita M, Travier N, Waterboer T, Margall N, Riboli E. Smoking as a major risk factor for cervical cancer and pre-cancer: results from the EPIC cohort. International journal of cancer. Journal international du cancer. Jul 15 2014;135(2):453-466. 40. Silva C, Almeida EC, Côbo Ede C, Zeferino VF, Murta EF, Etchebehere RM. A retrospective study on cervical intraepithelial lesions of low-grade and undetermined significance: evolution, associated factors and cytohistological correlation. Sao Paulo Med. 2014;132(2):92-6. 41. Tumours of the uterine cervix // WHO Classification of tumours of female reproductive organs / Edited by R.J. Kurman, M.L. Carcangiu, C.S. Herrington, R.H. Young. – Lyon: International agency for research on cancer, 2014. – P. 169-206. 42. .Turinetto, V., Giachino C.Multiple facets of histone variant H2AX: a DNA double-strandbreakmarker with several biological functions.// Nucleic AcidsRes. – 2015. – Vol. 43, N. 5. – P. 2489-2498. 43. Ueda Y. Postpartum outcome of cervical intraepithelial neoplasia in pregnant women determined by route of delivery / Y. Ueda, T. Enomoto, T. Miyatake // Reprod Sci. – 2009. –Vol 16. – 11. – P. 1034 – 1039. 44. Xavier-Júnior, JC. High-grade squamous intraepithelial lesions in pregnant and non-pregnant women / JC. Xavier-Júnior, RM. Dufloth //. – 2014. – Vol 175. – P.103-106.