FEATURES OF DETERMINATION OF PROGNOSTIC AND DIAGNICALLY SIGNIFICANT MARKERS IN THE BLOOD OF PATIENTS WITH PULMONARY TUBERCULOSIS

Rustamova S.A.; Muazzamov B.R.

doi:10.5281/zenodo.10041236

FEATURES OF DETERMINATION OF PROGNOSTIC AND DIAGNICALLY SIGNIFICANT MARKERS IN THE BLOOD OF PATIENTS WITH PULMONARY TUBERCULOSIS

25.10.2023 International Scientific Journal "Science and Innovation". Series D. Volume 2 Issue 10

Rustamova S.A., Muazzamov B.R.

Abstract. Throughout the world, the epidemiological situation with regard to tuberculosis remains difficult. Purpose of the study: to study the immunobiological properties of the organism in newly diagnosed patients with pulmonary tuberculosis. We conducted a study on the presence of prognostic and diagnostically significant markers in the blood serum of 30 patients with a verified diagnosis. A comparative group contains 15 practically healthy persons. All patients underwent general clinical, bacterioscopic examination, chest X-ray. It is determined the concentration of cytokines - TNF- α and CRP, VGF. Conclusions: A moderate increase in the level of CRP allows early detection of the course of the pathological process and as certain the formation of a systemic inflammatory response to activate phagocytosis. Correlation of a decrease in the concentration of TNF- α in the blood serum in patients with recurrent disease secondary to an increase in the level of VEGF in the same patients.

Keywords: blood markers, pulmonary tuberculosis, immunity, cytocynes

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