STATUS OF PARAMETERS OF SOME CYTOKINES IN SICK CHILDREN WITH PSORIASIS
28.08.2023
International Scientific Journal "Science and Innovation". Series D. Volume 2 Issue 8
Valiyev А.А., Khaitov К.N.
Abstract. Psoriasis is a chronic immune-associated disease of a multifactorial nature with a dominant role in the development of genetic factors, characterized by hyperproliferation of keratinocytes, impaired differentiation, immune reactions in the dermis and synovial membranes, an imbalance between pro-inflammatory and anti-inflammatory cytokines, chemokines; frequent pathological changes in the musculoskeletal system.
Keywords: musculoskeletal system, anti-inflammatory cytokines, chemokines
References:
1. Aripova T.U., Rizopulu A.P., Umarova A.A. Cytokines - regulators and effectors of the immune system //Method. recommendations. -Tashkent. –2005. –23с.
2. Bakulev A.L., Fitileva T.V., Novoderezhkina E.A. Psoriasis: clinical and epidemiological features and issues of therapy // Bulletin of dermatology and venereology. –2018. –Т.94. –№3. –С.67-76.
3. Evdokimov E.Yu., Ponezheva Zh.B., Svechnikova E.V., Sundukov A.V. Clinical and immunological features of psoriasis vulgaris in HIV-infected patients //Medical Council. –2021. –Т.21. –№2. –С.94-101.
4. Sobolev V.V., Chebysheva S.N., Geppe N.A. TNF-α gene expression in immune cells of patients with psoriasis and psoriatic arthritis //Medical Council. –2022. –Т.16. –№13. –С.6-10.
5. Khairutdinov V.R. Immunohistochemical analysis of the skin of patients with psoriasis // Cytokines and inflammation. –2012. –Т.11. –№3. –С.27-34.
6. Khairutdinov V.R., Belousova I.E., Samtsov A.V. Immune pathogenesis of psoriasis // Bulletin of dermatology and venereology. –2016. –№4. –С.20-26.
7. Dickel H., Bruckner T., Höxtermann S. et al. Fumaric acid ester-induced T-cell lymphopenia in the real-life treatment of psoriasis //J. Eur. Acad. Dermatol. Venereol. –2019. –V.33. –№5. –P.893-905.
8. Fantuzzi F., Del Giglio M., Gisondi P., Girolomoni G. Targeting tumor necrosis factor alpha in psoriasis and psoriatic arthritis //Expert Opin. Ther. Targets. –2008. –V.12. –№9. –P.1085-1096.
9. Kim J., Krueger J.G. The immunopathogenesis of psoriasis //Dermatol. Clin. –2015. –V.33. –№1. –Р.13-23.
10. Lowes M.A., Suarez-Farinas M., Krueger J.G. Immunology of psoriasis //Annu. Rev. Immunol. –2014. –V.32. –P.227-255.
11. Zhang M., Deng X., Guan X. et al. Herpes Simplex Virus Type 2 Infection- Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4 //Front. Immunol. –2018. –V.9. –P.29-32.
SCIENCE & INNOVATION