WHAT IS THE MECHANISM OF ACTION OF A PROTON PUMP INHIBITOR?

21.05.2023 International Scientific Journal "Science and Innovation". Series D. Volume 2 Issue 5

Azimbegova Sitora Nodirovna

Abstract. Pariet - PPI proton pump inhibitors with the active ingredient rabeprazole, after passing through the stomach, enter the small intestine, where they dissolve, after which they first enter the liver through the bloodstream, and then penetrate the membrane of the parietal cells of the gastric mucosa. goes and there they accumulate in the secretion. tubules. Here, at acidic pH, proton pump inhibitors are activated and become tetracyclic mechanism of action of proton pump inhibitors (Maev I.V. et al.)

Keywords: proton pump inhibitor, action, mechanism, types of proton pump inhibitors