GENETIC MARKERS FOR THE DEVELOPMENT OF DIABETIC RETINOPATHY

15.12.2022 International Scientific Journal "Science and Innovation". Series D. Volume 1 Issue 8

D.Jalalova , N.Normatova , F.Shernazarov

Abstract. Diabetic retinopathy is the most common microvascular complication of diabetes mellitus and occurs in all type 1 diabetic patients and in 75% of type 2 diabetic patients within 15 years of disease onset. Morphologically, diabetic retinopathy is manifested by the presence of microvascular lesions of the retina. Early changes include the appearance of microaneurysms, hemorrhages, hard and soft exudates, and hemodynamic disturbances. These clinical features are collectively referred to as non-proliferative diabetic retinopathy. Abnormal growth of new blood vessels, which often leads to preretinal and intravitreal hemorrhages, characterizes proliferative diabetic retinopathy.

Keywords: diabetes and inadequate glycemic control are the two most important factors in the development of retinopathy.