Abstract. It is stated the main stages of relationship between the Republic of Uzbekistan and the Republic of China are. The Republic of Uzbekistan is also interested in establishing mutually beneficial partnership with the PRC in the political, economic, trade, scientific and cultural spheres. Traditional friendly relationship has been established between the Republic of Uzbekistan and the Republic of China. It gives opportunity for both countries to conduct mutually beneficial and effective partnership on many issues of mutual interest. On May 11-13, 2017, the state visit of President Shavkat Mirziyoyev to the Republic of China raised Uzbekistan-China relationship to a new step. At the end of the negotiations, Shavkat Mirziyoyev and Xi Jinping signed the Joint Statement between the Republic of Uzbekistan and the Republic of China. During his visit to China, Shavkat Mirziyoyev signed 105 mutual documents which cost total 23 billion dollars.