Heredity, allergen anamnesis and seasonality of the disease were studied in 126 children with atopic dermatitis (AD) aged 3 months to 17 years. In many children with AD, worsening of the allergic history is a predictor of the development of atopic dermatitis. At the same time, the analysis of allergopathology among the patients' stomachs revealed that pollinosis (allergic rhinitis) is mainly found. It should also be noted that atopic dermatitis in children is characterized by recurrence and exacerbation of the disease in most cases in the autumn-winter season.
26.07.2023 Volume 2 Issue 7 View more Download
The study of the morphological characteristics of skin changes according to the results of dermatoscopy was provided in children aged 3 months to 17 years with several clinical forms of AD. It is advisable to use dermatoscopy to optimize the early diagnosis of ad in children, objectively assess the pathological process on the skin, predict the course of the disease, control the therapeutic effectiveness of the treatment process and the measures used. Comparing the results of dermatoscopy and the clinical picture increases the reliability of the information obtained during the examination.
26.07.2023 Volume 2 Issue 7 View more Download
The number of patients with congenital heart disease (CHD) is constantly growing all over the world and remains the most common pathology. Statistics of recent years indicate an increase in the number of children with septal heart defects and an increase in mortality. This article discusses the optimization of myocardial protection methods during radical correction in children with septal heart defects.
21.07.2023 Volume 2 Issue 7 View more Download
Meningiomas, a group of tumors originating from the meninges, have a wide range of morphological characteristics that determine the type and grade of malignancy. The study of anaplastic meningiomas is challenging because they resemble soft tissue malignancies. Immunostaining makes it possible not only to determine the cytogenetic source and the degree of malignancy of the tumor, but also to detect pathological proteins - transcription products of damaged DNA sections and give recommendations on the appointment of targeted therapy.
21.07.2023 Volume 2 Issue 7 View more Download
Knowledge about the prevalence of the cancer process and its microscopic signs helps to establish the stage of development of the disease, helps to assess the likelihood of tumor recurrence and provides information that will allow the doctor to predict the therapeutic effect. With vulvar cancer, the tumor often spreads along the length and by metastasis to the regional lymph nodes (inguinal, femoral), and then to the pelvic lymph nodes. In malignant tumors, the level of lymph node lesion, which can be determined by lymph node dissection, is of great importance for the choice of treatment method.
21.07.2023 Volume 2 Issue 7 View more Download
Cardiometabolic risk factors were studied in young patients with arterial hypertension against the background of abdominal obesity. The study involved 54 young patients with arterial hypertension of I-III degree, aged 18-44 years. It was found that the most pronounced cardiometabolic disorders, including changes in carbohydrate and lipid metabolism, were found in the group of young patients with abdominal obesity. In overweight young people, as well as in obese people, cardiometabolic changes can be detected, which makes it possible to diagnose these disorders in a timely manner and implement effective strategies for the primary prevention of cardiovascular and metabolic diseases.
16.07.2023 Volume 2 Issue 7 View more Download
This article analyzes the features of the international legal activities of the United Nations to ensure international cooperation for the protection of the natural environment. The author notes that the UN is important in the framework of international cooperation and allows countries to consolidate their efforts to overcome the consequences of environmental problems.
14.07.2023 Volume 2 Issue 7 View more Download
The study included materials from 76 operations (110 paraffin blocks) that were not treated with neoadjuvant treatments, since preoperative exposure to tumors could significantly affect the results of the study, which is why these samples were not included in the study. It was found that the high viral load of HPV in RV correlates with the presence of metastases to the lymph nodes, invasion of the stroma, the degree of differentiation, as well as lymphovascular invasion, while it is in no way related to the stage of the disease. PD-L1 receptor expression is more often observed in HPV negative RV patients compared to HPV positive ones (7.8 vs. 3.7 p=0.03), while HPV positive patients were more likely to have STK11 mutation. At the same time, the PIK3CAE545 mutation occurred with the same frequency between the two groups of RV patients.
12.07.2023 Volume 2 Issue 7 View more Download
The article presents the results of studying the features of metabolic disorders in patients with COVID-19 in the acute phase of the disease. The study used data of 31 patients in the acute period of coronavirus infection caused by COVID-19. The average age of patients was 56.4±12.8 years (from 32 to 80 years), among them 13 (41.9%) were men and 18 (58.1%) were women. The data obtained indicate that obesity and dyslipidemia, in particular, high lipid levels are more common in patients with a moderate disease course. But at the same time, some metabolic disorders are also 1.2-1.6 times more common in patients with a moderate course of coronavirus infection compared with a mild course (respectively, blood pressure ≥ 140/90 mmHg: 23.5% vs. 14.3%; TG ≥1.7 mmol/L: 47.1% vs. 28.6%; HDL <1.0 mmol/L: 64.7 vs. 28.6%; fasting glucose ≥6.1 mmol/L: 35.3% vs. 28.6%).
07.07.2023 Volume 2 Issue 7 View more Download
Writing to this article assist the Decree No. PD-3968 of the President of Uzbekistan dated October 12, 2018 “On measures to regulate the field of folk medicine in the Republic of Uzbekistan”, PD-5707 dated April 10, 2019 “On measures to further develop the pharmaceutical industry of the republic in 2019-2021” Decree No. PD-4670 dated April 10, 2020 “On measures for the protection of wild medicinal plants, cultivation, processing and rational use of available resources” in preventing various diseases in the human body, a the significance of several medicinal plants was studied.
05.07.2023 Volume 2 Issue 7 View more Download
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